Metal-organic frameworks (MOFs) structural properties and electrochemical detection capability for cancer biomarkers

被引：27
作者：
Mohan, Brij [1 ]
Dhiman, Diksha [2 ]
Virender [2 ]
Mehak [2 ]
Priyanka [3 ]
Sun, Qiming [4 ]
Jan, Masood [5 ]
Singh, Gurjaspreet [3 ]
Raghav, Neera [2 ]
机构：
[1] Univ Lisbon, Inst Mol Sci, Ctr Quim Estrutural, Inst Super Tecn, Ave Rovisco Pais, P-1049001 Lisbon, Portugal
[2] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India
[3] Panjab Univ, Ctr Adv Studies, Dept Chem, Chandigarh 160014, India
[4] Jimei Univ, Coll Ocean Food & Biol Engn, 185 Yinjiang Rd, Xiamen 361021, Peoples R China
[5] Henan Univ, Sch Life Sci, State Key Lab Cotton Biol, Key Lab Plant Stress Biol, 85 Minglun St, Kaifeng 475001, Peoples R China
来源：
MICROCHEMICAL JOURNAL | 2023年 / 193卷
关键词：
MOFs; Porosity; Surface area; Cancer biomarkers; Electrochemical biosensors; ULTRASENSITIVE DETECTION; REVERSE SYNTHESIS; LAYER; PLATFORM; IMMUNOSENSOR; BIOSENSORS; CO2;
D O I：
10.1016/j.microc.2023.108956
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Metal-organic frameworks (MOFs) are a prominent porous material for cancer biomarkers detection. They are enriched with unique features of permanent porosity and tunable pore size, leading to their efficient use in biosensing. In this review, we have summarized and studied MOF materials for the electrochemical detection of cancer biomarkers. First, insight into the tunable porosity and surface areas have been discussed to explore the applicability of MOFs. MOFs porosity and functional sites are critical to the development of the sensor. Then, MOF biosensors for target cancer biomarkers detection have been discussed. In addition, the MOFs biosensors challenges and future direction are discussed to provide next-generation biosensors.
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页数：13
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