Visible-Light-Promoted Click [3+2] Cycloaddition of Aziridine with Alkyne: An Efficient Synthesis of Dihydropyrrolidine

被引：5

作者：

Kapoor, Ritu ^{[1
]}

Chawla, Ruchi ^{[2
]}

Verma, Ankit ^{[3
]}

Keshari, Twinkle ^{[4
]}

Siddiqui, I. R. ^{[3
]}

机构：

[1] Univ Allahabad, Dept Chem, Ayush & Green Technol Res Lab, Prayagraj 211002, India

[2] Motilal Nehru Natl Inst Technol Allahabad, Dept Chem, Polymer Res Lab, Prayagraj 211004, India

[3] Univ Allahabad, Dept Chem, Lab Green Chem, Prayagraj 211002, India

[4] Veer Kunwar Singh Univ, Dept Chem, Arrah, India

来源：

SYNLETT | 2023年 / 34卷 / 13期

关键词：

aziridine; alkyne; dihydropyrrolidine; visible light; click chemistry; photoredox catalysis; PHOTOREDOX CATALYSIS; FACILE SYNTHESIS; N-HETEROCYCLES; ANNULATION; CYCLOPROPANES; PYRROLIDINES; ISOCYANIDES; DERIVATIVES; CYCLIZATION; PYRROLE;

D O I：

10.1055/a-2099-6309

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A photocatalytic [3+2] cycloaddition of aziridines with activated alkynes is reported under visible-light irradiation in the presence of ruthenium catalyst. This chemical transformation provides polysubstituted pyrrolidines in good yields based on the click chemistry philosophy. The reaction successfully represents a primary trial of cyclocarboamination through photocascade catalysis combining energy transfer and redox neutral reactions.

引用

页码：1621 / 1625

页数：5

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