Prism SPR Glucose Sensor Based on Gold Nanoparticle/Gold Film Coupling Enhanced SPR

被引：17

作者：

Fang, Wu ^{[1
]}

Ding, Liyun ^{[2
]}

Zhang, Yumei ^{[1
]}

Li, Haijun ^{[3
]}

机构：

[1] Wuhan Univ Technol, Natl Engn Lab Fiber Opt Sensing Technol, Wuhan 430070, Peoples R China

[2] Lanzhou Univ, Sch Phys Sci & Technol, Lanzhou 730000, Peoples R China

[3] Inner Mongolia Agr Univ, Coll Vet Med, Hohhot 010018, Peoples R China

来源：

IEEE SENSORS JOURNAL | 2023年 / 23卷 / 12期

基金：

中国国家自然科学基金;

关键词：

Coupling enhancement effect; glucose sensor; gold nanoparticle (AuNPs); surface plasmon resonance (SPR); SURFACE-PLASMON RESONANCE; SENSITIVE MEMBRANE; BIOSENSOR; OXIDASE; IMMOBILIZATION; DISEASE; ENZYME;

D O I：

10.1109/JSEN.2023.3268310

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A novel glucose sensor based on gold nanoparticles (AuNPs) enhanced surface plasmon resonance (SPR) is proposed for the accurate detection of glucose concentration. The coupling enhancement effect of localized SPR (LSPR) of AuNPs and SPR of gold film can improve the refractive index (RI) sensitivity of the sensor. The specific reaction between glucose and glucose oxidase (GOD) causes a change in the RI of the glucose solution microenvironment and eventually leads to a drift in the resonance angle. Field-emission scanning electron microscope (SEM) was used to characterize the GOD before and after immobilization, and the effect of different concentrations of GOD on the detection of glucose by the sensor was investigated. The experimental results showed that the proposed sensor surface out excellent performance in terms of sensitivity [0.8633 degrees/(mg/mL)].

引用

页码：12477 / 12484

页数：8

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