Stereoselective β-Arylation of Enol Ethers by a Pd-Catalyzed Fujiwara-Moritani Coupling of α-Oxyacrylates

被引：0

作者：

Traboulsi, Iman ^{[1
]}

Hachem, Mahmoud ^{[1
]}

Schneider, Cedric ^{[1
]}

Hoarau, Christophe ^{[1
]}

机构：

[1] Univ Rouen Normandie, Normandie Univ, INSA Rouen Normandie, CNRS,INC3M FR 3038,COBRA UMR 6014, F-76000 Rouen, France

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 27卷 / 04期

关键词：

C-H activation; beta-arylation; Pd catalysis; dehydrogenative Heck reaction; enol ethers; ELECTRON-RICH OLEFINS; VINYL ETHERS; OXIDATIVE HECK; BOND FORMATION; MIZOROKI-HECK; C-C; ARYL; CARBON; MECHANISM; HALIDES;

D O I：

10.1002/ejoc.202301074

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, Pd(II)-catalyzed dehydrogenative Heck coupling of 2-oxyacrylates with arenes for the stereocontrolled production of (Z)-beta-arylated vinyl ethers is reported. This methodology offers a straightforward and step-economical route to the synthesis of attractive beta-arylated alpha-oxy alpha,beta-unsaturated carboxylates family which emerged as a relevant class of building blocks with different applications.

引用

页数：6

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