Impact of Cardiac Motion on coronary artery calcium scoring using a virtual non-iodine algorithm on photon-counting detector CT: a dynamic phantom study

被引:8
作者
Fink, Nicola [1 ,2 ]
Zsarnoczay, Emese [1 ,3 ]
Schoepf, U. Joseph [1 ]
O'Doherty, Jim [1 ,4 ]
Halfmann, Moritz C. [5 ]
Allmendinger, Thomas [6 ]
Hagenauer, Junia [6 ,7 ]
Griffith III, Joseph P. [1 ]
Vecsey-Nagy, Milan [1 ,8 ]
Pinos, Daniel [1 ]
Ebersberger, Ullrich [9 ]
Ricke, Jens [2 ]
Varga-Szemes, Akos [1 ]
Emrich, Tilman [1 ,5 ,10 ]
机构
[1] Med Univ South Carolina, Dept Radiol & Radiol Sci, Div Cardiovasc Imaging, 25 Courtenay Dr, Charleston, SC 29425 USA
[2] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Radiol, Marchioninistr 15, D-81377 Munich, Germany
[3] Semmelweis Univ, Med Imaging Ctr, Korany Sandor Utca 2, H-1083 Budapest, Hungary
[4] Siemens Med Solut, Malvern, PA 19355 USA
[5] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Diagnost & Intervent Radiol, Langenbeckstr 1, D-55131 Mainz, Germany
[6] Siemens Healthcare GmbH, Siemensstr 1, D-91301 Forchheim, Germany
[7] Friedrich Alexander Univ Erlangen Nuremberg, Fac Med, Krankenhausstr 12, D-91054 Erlangen, Germany
[8] Semmelweis Univ, Heart & Vasc Ctr, MTA SE Cardiovasc Imaging Res Grp, Varosmajor Utca 68, H-1122 Budapest, Hungary
[9] Ludwig Maximilians Univ Munchen, Munich Univ Clin, Dept Cardiol, D-80636 Munich, Germany
[10] German Ctr Cardiovasc Res, D-55131 Mainz, Germany
关键词
Coronary artery calcium scoring; Photon-counting detector CT; Virtual non-iodine algorithm; Virtual non-contrast algorithm; Cardiac motion; In-vessel attenuation; MULTIDETECTOR COMPUTED-TOMOGRAPHY; HEART-RATE; DUAL-SOURCE; CALCIFICATION DENSITY; ROW CT; ANGIOGRAPHY; QUANTIFICATION; SCORES; ATTENUATION; MULTIVENDOR;
D O I
10.1007/s10554-023-02912-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This study assessed the impact of cardiac motion and in-vessel attenuation on coronary artery calcium (CAC) scoring using virtual non-iodine (VNI) against virtual non-contrast (VNC) reconstructions on photon-counting detector CT. Two artificial vessels containing calcifications and different in-vessel attenuations (500, 800HU) were scanned without (static) and with cardiac motion (60, 80, 100 beats per minute [bpm]). Images were post-processed using a VNC and VNI algorithm at 70 keV and quantum iterative reconstruction (QIR) strength 2. Calcium mass, Agatston scores, cardiac motion susceptibility (CMS)-indices were compared to physical mass, static scores as well as between reconstructions, heart rates and in-vessel attenuations. VNI scores decreased with rising heart rate (p < 0.01) and showed less underestimation than VNC scores (p < 0.001). Only VNI scores were similar to the physical mass at static measurements, and to static scores at 60 bpm. Agatston scores using VNI were similar to static scores at 60 and 80 bpm. Standard deviation of CMS-indices was lower for VNI-based than for VNC-based CAC scoring. VNI scores were higher at 500 than 800HU (p < 0.001) and higher than VNC scores (p < 0.001) with VNI scores at 500 HU showing the lowest deviation from the physical reference. VNI-based CAC quantification is influenced by cardiac motion and in-vessel attenuation, but least when measuring Agatston scores, where it outperforms VNC-based CAC scoring.
引用
收藏
页码:2083 / 2092
页数:10
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