Chemical Constituents from The Leaves and Twigs of Magnolia Decidua

被引：0

作者：

Zhou, Qi ^{[1
]}

Wan, Jiang ^{[1
]}

Jiang, Chun-Xiao ^{[1
,2
]}

Tong, Ying-Peng ^{[1
]}

Xie, Zhen-Da ^{[1
]}

Wang, Ting ^{[1
]}

Xiao, Dao-An ^{[3
]}

Xiao, Zhi-Yong ^{[4
]}

Hu, Jin-Feng ^{[1
,2
]}

机构：

[1] Taizhou Univ, Zhejiang Prov Key Lab Plant Evolutionary Ecol & C, Sch Pharmaceut Sci, Inst Nat Med & Hlth Prod, Taizhou 318000, Zhejiang, Peoples R China

[2] Fudan Univ, Sch Pharm, Dept Nat Med, Shanghai 201203, Peoples R China

[3] Yichun Univ, Coll Chem & Bioengn, Yichun 336000, Jiangxi, Peoples R China

[4] Yichun Acad Sci, Yichun 336000, Jiangxi, Peoples R China

来源：

RECORDS OF NATURAL PRODUCTS | 2023年 / 17卷 / 03期

关键词：

Magnoliaceae; Magnolia decidua; phenolic glycoside; manglycoside A; anti-inflammatory; PHENOLIC-COMPOUNDS; NEOLIGNANS; LIGNANS; BARK;

D O I：

10.25135/rnp.376.2207.2525

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A previously undescribed phenolic glycoside (manglycoside A, 1), as well as 16 identified compounds (2-17), were isolated from the leaves and twigs of the 'vulnerable' plant Magnolia decidua (Magnoliaceae). Comprehensive spectroscopic investigation and chemical transformations revealed the structure of the previously unknown compound 1. Among the isolates, honokiol ( 6) and liriodenine (14) were discovered to exhibit anti-inflammatory activities in LPS-induced RAW 264.7 cells via reducing nitric oxide (NO) formation, with IC50 values of 4.3 and 17.3 mu M, correspondingly.

引用

页码：509 / 515

页数：7

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