An unusual presentation of a primary lung adenocarcinoma: A case report

被引:0
作者
Killoran, Callie [1 ,3 ]
Tabone, Renee A. [1 ,2 ]
Olive, Emily [1 ]
Bell-Allen, Nicholas [1 ]
Wilson, Katherine [1 ,2 ]
机构
[1] Sunshine Coast Univ Hosp, Dept Surg, 6 Doherty St, Birtinya, Qld 4575, Australia
[2] Griffith Univ, Sch Med & Dent, Parklands Dr,Southport,Gold Coast Campus, Brisbane, Qld 4222, Australia
[3] Sunshine Coast Univ Hosp, Clin Dept Off, Main Hosp Bldg,Level 1,6 Doherty St, Birtinya, Qld 4575, Australia
关键词
Lung cancer; Metastasis; Gastrointestinal metastasis; Surgical resection; Tumour markers; Case report; SMALL-BOWEL METASTASES; GASTROINTESTINAL METASTASIS; CANCER; CARCINOMA;
D O I
10.1016/j.ijscr.2023.108967
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction and importance: Lung cancer is one of the most common malignancies worldwide and common sites of metastasis are to brain, liver, adrenal glands, and bones [1]. Metastasis to the gastrointestinal (GI) tract is extremely rare (<1%) and the most common site is the small intestine [5].Case presentation: A 60-year-old female referred for intermittent colicky abdominal pain and diarrhoea, with cross-sectional imaging showing a distal small bowel mass with lymphadenopathy. Malignancy workup revealed an additional mediastinal mass and raised tumour marker carcinoembryonic antigen (CEA). Bronchoscopy confirmed primary lung adenocarcinoma of the mediastinal mass. Given the raised CEA, evolving obstructive symptoms, and concerns for synchronous lung and gastrointestinal primaries, the patient proceeded to have a small bowel resection leading to the diagnosis of a GI lung metastasis.Clinical discussion: If Symptomatic, suggested treatment of lung metastasis to the GI tract is surgical resection. Current evidence suggests that in isolated GI metastases, resection may have a therapeutic benefit and an as-sociation with overall survival rate.Conclusion: In patients with symptomatic or isolated GI lung metastasis, surgical resection should be considered for treatment and management of metastatic disease. The role of tumour marker CEA in primary lung adeno-carcinoma is unclear.
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共 11 条
[1]   The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines [J].
Agha, Riaz A. ;
Franchi, Thomas ;
Sohrabi, Catrin ;
Mathew, Ginimol ;
Kerwan, Ahmed ;
Thoma, Achilles ;
Beamish, Andrew J. ;
Noureldin, Ashraf ;
Rao, Ashwini ;
Vasudevan, Baskaran ;
Challacombe, Ben ;
Perakath, Benjamin ;
Kirshtein, Boris ;
Ekser, Burcin ;
Pramesh, C. S. ;
Laskin, Daniel M. ;
Machado-Aranda, David ;
Miguel, Diana ;
Pagano, Duilio ;
Millham, Frederick H. ;
Roy, Gaurav ;
Kadioglu, Huseyin ;
Nixon, Iain J. ;
Mukhejree, Indraneil ;
McCaul, James A. ;
Ngu, James Chi-Yong ;
Albrecht, Joerg ;
Gomez Rivas, Juan ;
Raveendran, Kandiah ;
Derbyshire, Laura ;
Ather, M. Hammad ;
Thorat, Mangesh A. ;
Valmasoni, Michele ;
Bashashati, Mohammad ;
Chalkoo, Mushtaq ;
Teo, Nan Zun ;
Raison, Nicholas ;
Muensterer, Oliver J. ;
Bradley, Patrick James ;
Goel, Prabudh ;
Pai, Prathamesh S. ;
Afifi, Raafat Yahia ;
Rosin, Richard David ;
Coppola, Roberto ;
Klappenbach, Roberto ;
Wynn, Rolf ;
De Wilde, Rudy Leon ;
Surani, Salim ;
Giordano, Salvatore ;
Massarut, Samuele .
INTERNATIONAL JOURNAL OF SURGERY, 2020, 84 :226-230
[2]   Small bowel metastases from primary carcinoma of the lung: Clinical findings and outcome [J].
Berger, A ;
Cellier, C ;
Daniel, C ;
Kron, C ;
Riquel, M ;
Barbier, JP ;
Cugnenc, PH ;
Landi, B .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 1999, 94 (07) :1884-1887
[3]   Gastrointestinal metastasis of primary lung cancer: An analysis of 366 cases [J].
Hu, Yue ;
Feit, Noah ;
Huang, Yanqin ;
Xu, Wenhong ;
Zheng, Shu ;
Li, Xiuzhen .
ONCOLOGY LETTERS, 2018, 15 (06) :9766-9776
[4]  
Kim Jae Jun, 2015, Korean J Thorac Cardiovasc Surg, V48, P335, DOI 10.5090/kjtcs.2015.48.5.335
[5]   Gastrointestinal metastasis of lung cancer with special emphasis on a long-term survivor after operation [J].
Kim, Min Soo ;
Kook, Eun Hee ;
Ahn, Se Han ;
Jeon, Se Young ;
Yoon, Jung Ho ;
Han, Min Sung ;
Kim, Cheol Hyeon ;
Lee, Jae Cheol .
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2009, 135 (02) :297-301
[6]  
Kim So Yeon, 2009, AJR Am J Roentgenol, V193, pW197, DOI 10.2214/AJR.08.1907
[7]   Role of surgical intervention in managing gastrointestinal metastases from lung cancer [J].
Lee, Po-Chu ;
Lo, Chiao ;
Lin, Ming-Tsan ;
Liang, Jin-Tung ;
Lin, Been-Ren .
WORLD JOURNAL OF GASTROENTEROLOGY, 2011, 17 (38) :4314-4320
[8]   Small bowel metastases in non-small cell lung cancer [J].
Stenbygaard, LE ;
Sorensen, JB .
LUNG CANCER, 1999, 26 (02) :95-101
[9]   Analysis of gastrointestinal metastasis of primary lung cancer: Clinical characteristics and prognosis [J].
Taira, Naohiro ;
Kawabata, Tsutomu ;
Gabe, Atsushi ;
Furugen, Tomonori ;
Ichi, Takaharu ;
Kushi, Kazuaki ;
Yohena, Tomofumi ;
Kawasaki, Hidenori ;
Higuchi, Daisuke ;
Chibana, Kenji ;
Fujita, Kaori ;
Nakamoto, Atsushi ;
Owan, Isoko ;
Kuba, Mutsuo ;
Ishikawa, Kiyoshi .
ONCOLOGY LETTERS, 2017, 14 (02) :2399-2404
[10]   Global Cancer Statistics, 2012 [J].
Torre, Lindsey A. ;
Bray, Freddie ;
Siegel, Rebecca L. ;
Ferlay, Jacques ;
Lortet-Tieulent, Joannie ;
Jemal, Ahmedin .
CA-A CANCER JOURNAL FOR CLINICIANS, 2015, 65 (02) :87-108