A case of squamous cell carcinoma of the breast achieved a pathological complete response after dose-dense AC plus dose-dense PTX

被引：0

作者：

Araki, Misato ^{[1
]}

Matsui, Koshi ^{[1
]}

Takagi, Kohji ^{[2
]}

Kanaya, Emi ^{[1
]}

Sekine, Shinichi ^{[1
]}

Nagasawa, Shiho ^{[1
]}

Watanabe, Toru ^{[1
]}

Miwa, Takeshi ^{[1
]}

Hirano, Katsuhisa ^{[1
]}

Igarashi, Takamichi ^{[1
]}

Tanaka, Haruyoshi ^{[1
]}

Shibuya, Kazuto ^{[1
]}

Hashimoto, Isaya ^{[1
]}

Hojo, Shozo ^{[1
]}

Yoshioka, Isaku ^{[1
]}

Okumura, Tomoyuki ^{[1
]}

Hirabayashi, Kenichi ^{[2
]}

Fujii, Tsutomu ^{[1
]}

机构：

[1] Univ Toyama, Fac Med, Dept Surg & Sci, Acad Assembly, 2630, Sugitani, Toyama 9300194, Japan

[2] Univ Toyama, Fac Med, Dept Diagnost Pathol, Acad Assembly, 2630, Sugitani, Toyama 9300194, Japan

来源：

SURGICAL CASE REPORTS | 2023年 / 9卷 / 01期

关键词：

Squamous cell carcinoma of the breast; Pathological complete response; Neoadjuvant chemotherapy; Breast-conserving surgery; NEOADJUVANT CHEMOTHERAPY; PACLITAXEL; CANCER;

D O I：

10.1186/s40792-023-01719-3

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BackgroundSquamous cell carcinoma (SCC) of the breast is a rare form of breast cancer, accounting for approximately 0.1% of all breast cancers. It is known for its rapid tumor growth and poor prognosis with no established treatment.Case presentationA 56-year-old woman was diagnosed with breast SCC with axillary, supraclavicular and internal thoracic lymph node metastases. She received neoadjuvant chemotherapy (NAC) with dose-dense doxorubicin and cyclophosphamide (AC) followed by dose-dense paclitaxel (PTX). This treatment resulted in a pathological complete response (pCR) after breast-conserving surgery. The patient was then treated with radiotherapy. She remained free of recurrence for three years postoperatively.ConclusionsWe report a rare case of breast SCC treated with preoperative dose-dense chemotherapy, resulting in pCR and allowing breast-conserving surgery.

引用

页数：5

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