Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis

被引：4

作者：

Akiki, Elias ^{[1
]}

Ahmad, Ali ^{[1
,2
]}

El-Am, Edward A. ^{[1
]}

Casanegra, Ana I. ^{[1
]}

Klarich, Kyle W. ^{[1
]}

Kurmann, Reto ^{[1
]}

机构：

[1] Mayo Clin, Dept Cardiovasc Med, Rochester, MN 55902 USA

[2] St Louis Univ, Dept Internal Med, Sch Med, St Louis, MO USA

来源：

FRONTIERS IN CARDIOVASCULAR MEDICINE | 2023年 / 10卷

关键词：

non-bacterial thrombotic endocarditis; anticoagulation; embolic stroke; heparin; warfarin; DOAC; apixaban; CANCER-PATIENTS; PATHOGENESIS; DIAGNOSIS;

D O I：

10.3389/fcvm.2023.1208190

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy.

引用

页数：4

共 15 条

[1] Nonbacterial Thrombotic Endocarditis: Presentation, Pathophysiology, Diagnosis and Management [J].

Al Chalaby, Shahad ;

Makhija, Rakhee R. ;

Sharma, Ajay N. ;

Majid, Muhammad ;

Aman, Edris ;

Venugopal, Sandhya ;

Amsterdam, Ezra A. .

REVIEWS IN CARDIOVASCULAR MEDICINE, 2022, 23 (04)

[2] Transesophageal echocardiography is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke [J].

de Bruijn, Sebastiaan F. T. M. ;

Agema, Willem R. P. ;

Lammers, Gert Jan ;

van der Wall, Ernst E. ;

Wolterbeek, Ron ;

Holman, Eduard R. ;

Bollen, Edward L. E. M. ;

Bax, Jeroen J. .

STROKE, 2006, 37 (10) :2531-2534

[3] Cardiac valvular vegetations in cancer patients: A prospective echocardiographic study of 200 patients [J].

Edoute, Y ;

Haim, N ;

Rinkevich, D ;

Brenner, B ;

Reisner, SA .

AMERICAN JOURNAL OF MEDICINE, 1997, 102 (03) :252-258

[4] Nonbacterial thrombotic endocarditis in cancer patients: Pathogenesis, diagnosis, and treatment [J].

el-Shami, Khaled ;

Griffiths, Elizabeth ;

Streiff, Michael .

ONCOLOGIST, 2007, 12 (05) :518-523

[5] Direct oral anticoagulant (DOAC) versus low-molecular-weight heparin (LMWH) for treatment of cancer associated thrombosis (CAT): A systematic review and meta-analysis [J].

Li, Ang ;

Garcia, David A. ;

Lyman, Gary H. ;

Carrier, Marc .

THROMBOSIS RESEARCH, 2019, 173 :158-163

[6] Nonbacterial Thrombotic Endocarditis Pathogenesis, Diagnosis, and Management [J].

Liu, Joshua ;

Frishman, William H. .

CARDIOLOGY IN REVIEW, 2016, 24 (05) :244-247

[7] NONBACTERIAL THROMBOTIC ENDOCARDITIS - A REVIEW [J].

LOPEZ, JA ;

ROSS, RS ;

FISHBEIN, MC ;

SIEGEL, RJ .

AMERICAN HEART JOURNAL, 1987, 113 (03) :773-784

[8] A first described case of cancer-associated non-bacterial thrombotic endocarditis in the era of direct oral anticoagulants [J].

Mantovani, F. ;

Navazio, A. ;

Barbieri, A. ;

Boriani, G. .

THROMBOSIS RESEARCH, 2017, 149 :45-47

[9]

Mayo Clinic, 2022, PEM INTR ROUT

[10] Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial [J].

Melloni, Chiara ;

Dunning, Allison ;

Granger, Christopher B. ;

Thomas, Laine ;

Khouri, Michel G. ;

Garcia, David A. ;

Hylek, Elaine M. ;

Hanna, Michael ;

Wallentin, Lars ;

Gersh, Bernard J. ;

Douglas, Pamela S. ;

Alexander, John H. ;

Lopes, Renato D. .

AMERICAN JOURNAL OF MEDICINE, 2017, 130 (12) :1440-+

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