Association of Sodium and Sugar-Sweetened Beverage Intake With Cardiovascular Disease Risk Factors in Adolescents and Young Adults With Obesity

被引:4
作者
Ong, Jason [1 ]
Roem, Jennifer [2 ]
Ducharme-Smith, Kirstie [3 ]
Vizthum, Diane [4 ]
Lu, Mengyang [5 ]
Agrawal, Pranjal [1 ]
Urbina, Elaine M. M. [6 ]
Brady, Tammy M. M. [1 ,7 ]
机构
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
[3] Rady Childrens Hosp, San Diego, CA USA
[4] Univ Delaware, Newark, DE USA
[5] Johns Hopkins Inst Clin & Translat Res, Baltimore, MD USA
[6] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH USA
[7] Johns Hopkins Sch Med, David M Rubenstein Child Hlth Bldg, 200 North Wolf, Baltimore, MD 21287 USA
关键词
sodium; sugar-sweetened beverage; artificial sweetened beverage; blood pressure; adiposity; DIETARY-SODIUM; BLOOD-PRESSURE; METABOLIC SYNDROME; CHILDHOOD OBESITY; SALT INTAKE; CONSUMPTION; CHILDREN; EPIDEMIOLOGY; WEIGHT; HEALTH;
D O I
10.1177/00099228231186666
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Cardiovascular disease (CVD) risk factors in children have increased in prevalence. Dietary intake may modify risk. Data collected during a randomized trial testing the effect of a behavioral intervention on adiposity, blood pressure (BP), and left ventricular mass index (LVMI) were analyzed using multivariable regression to determine independent associations of sodium, sugar-sweetened beverage (SSB), and artificially sweetened beverage (ASB) intake with outcomes. High sodium intake (& GE;3.5 g) was associated with hypertensive BP (odds ratio 12.8; P = .027) in minimally adjusted models. High SSB intake (& GE;4 oz) was independently associated with body mass index z-score (& beta; = .34; P = .035) and waist circumference z-score (& beta; = .49; P = .022) in fully adjusted models. Any ASB intake was associated with LVMI in fully adjusted model (% change 38.22; P = .004). There was no effect modification between sodium and SSB on outcomes. Dietary factors explored in this study independently impacted CVD risk. Further effect measure modification should be explored in larger cohorts.
引用
收藏
页码:669 / 679
页数:11
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