Long-term patient-reported outcomes after reconstructive surgery for head and neck cancer: A systematic review

被引：17

作者：

van Rooij, Joep A. F. ^{[1
]}

Roubos, Jantien ^{[2
]}

Peeters, Noelle J. M. C. Vrancken ^{[2
]}

Rijken, Bianca F. M. ^{[2
]}

Corten, Eveline M. L. ^{[2
]}

Mureau, Marc A. M. ^{[2
]}

机构：

[1] Maastricht Univ Med Ctr MUMC, Dept Plast Reconstruct & Hand Surg, Maastricht, Limburg, Netherlands

[2] Erasmus MC, Canc Inst, Univ Med Ctr Rotterdam, Dept Plast & Reconstruct Surg, POB 2040, NL-3000 CA Rotterdam, South Holland, Netherlands

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2023年 / 45卷 / 09期

关键词：

head and neck cancer; patient-reported outcome measures; quality of life; reconstructive surgery; systematic review; QUALITY-OF-LIFE; FREE-FLAP RECONSTRUCTION; FOREARM FREE-FLAP; ORAL-CANCER; ONCOLOGIC SURGERY; MICROVASCULAR RECONSTRUCTION; MYOCUTANEOUS FLAP; SURVIVORS; DEFECTS; HAD;

D O I：

10.1002/hed.27450

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Current literature on reconstruction after head and neck cancer (HNC) focusses on short-term patient-reported outcomes (PROs), while there is a need for knowledge on long-term consequences. Embase, Medline, Web of Science, and Cochrane were searched for studies on health-related quality of life (HRQoL) after HNC reconstruction, using validated PROMs in at least 50 patients, and a follow-up of more than 1 year. Thirty studies were included, comprising 2358 patients with a follow-up between one and 10 years. The most used questionnaire was the UW-QoL v4. Reconstructive surgery was generally followed by diminished oral function, worsened by radiotherapy. Patients experienced anxiety and fear of cancer recurrence. However, there was a progressive decrease in pain over time with some flaps having more favorable HRQoL outcomes. Age and bony tumor involvement were not related to postoperative HRQoL. These results may lead to better patient counseling and expectation management of HNC patients.

引用

页码：2469 / 2477

页数：9

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