Olfactory dysfunction and SARS-CoV2

被引：1

作者：

Bonfils, Pierre ^{[1
]}

机构：

[1] Acad Med, 16 Rue Bonaparte, F-75006 Paris, France

来源：

BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE | 2023年 / 207卷 / 08期

关键词：

COVID-19; SARS Virus; Olfaction Disorders; Anosmia; COVID-19; SMELL;

D O I：

10.1016/j.banm.2022.11.019

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infection with a new coronavirus (SARS-CoV-2), the first case of which was described on December 8, 2019 in Wuhan, led the WHO to recognize the development of a considerable pandemic (COVID-19) marked by the importance of smell disorders. The prevalence and evolutionary profile of smell disorders vary according to the type of SARS-CoV-2 variant. With the first D614G mutation (Wuhan), the dysosmia prevalence was evaluated between 48% and 61%, dropping to less than 15% with the omicron variant. The evolution of olfactory loss is favorable in nearly 95% of cases after two years of evolution. The sequelae are marked, in addition to anosmia, by the frequency of parosmia. No treatment has really shown any effectiveness. The pathophysiology is dominated by damage to the olfactory neuroepithelium. The clinical profile of dysosmias linked to SARS-CoV-2 is similar to that of the classic post-viral anosmias known before COVID-19.

引用

页码：1075 / 1083

页数：9

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