First sequenced cases of Omicron BA.2 sublineage in Ecuador

被引：0

作者：

Andrade-Molina, D. A. ^{[1
]}

Morey-Leon, G. A. ^{[2
]}

Munoz-Mawyin, K. E. ^{[1
]}

Cruz-Fatuly, F. F. ^{[1
]}

Fernandez-Cadena, J. C. ^{[3
]}

Cardenas, P. ^{[4
]}

机构：

[1] Univ Espiritu Santo, Fac Hlth Sci, Om Sci Lab, Samborondon, Ecuador

[2] Univ Guayaquil, Fac Hlth Sci, Guayaquil, Ecuador

[3] Labs INTERLAB, Guayaquil, Ecuador

[4] Univ San Francisco Quito, Inst Microbiol, Quito, Ecuador

来源：

VIRUS RESEARCH | 2023年 / 334卷

关键词：

SARS-CoV-2; Omicron; BA; 2; Ecuador;

D O I：

10.1016/j.virusres.2023.199169

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The largest wave of infection with SARS-CoV-2 virus in Ecuador was observed in mid-December 2021 and early January 2022, driven by B.1.1.529/BA (Omicron) variant. During the second half of March, an increase in the number of daily cases was observed and coincided with the emergence of the BA.2 variant, which we describe in the present study. The first sequenced five cases of SARS-CoV-221L/BA.2 in Ecuador were identified using variant specific genotyping by qPCR and confirmed by whole genome sequencing (WGS). The first sequenced Ecuadorian BA.2 isolate was obtained from a person with international travel history who became symptomatic 3 days after travelling, whereas in the other cases no travel history was recorded.

引用

页数：5

共 30 条

[1] Implications of the Novel Mutations in the SARS-CoV-2 Genome for Transmission, Disease Severity, and the Vaccine Development [J].

Akkiz, Hikmet .

FRONTIERS IN MEDICINE, 2021, 8

[2] Investigating the Extent of Primer Dropout in SARS-CoV-2 Genome Sequences During the Early Circulation of Delta Variants [J].

Borcard, Loic ;

Gempeler, Sonja ;

Miani, Miguel A. Terrazos ;

Baumann, Christian ;

Graedel, Carole ;

Dijkman, Ronald ;

Suter-Riniker, Franziska ;

Leib, Stephen L. ;

Bittel, Pascal ;

Neuenschwander, Stefan ;

Ramette, Alban .

FRONTIERS IN VIROLOGY, 2022, 2

[3] Unusual N Gene Dropout and Ct Value Shift in Commercial Multiplex PCR Assays Caused by Mutated SARS-CoV-2 Strain [J].

Bozidis, Petros ;

Tsaousi, Eleni T. ;

Kostoulas, Charilaos ;

Sakaloglou, Prodromos ;

Gouni, Athanasia ;

Koumpouli, Despoina ;

Sakkas, Hercules ;

Georgiou, Ioannis ;

Gartzonika, Konstantina .

DIAGNOSTICS, 2022, 12 (04)

[4] Multiple Occurrences of a 168-Nucleotide Deletion in SARS-CoV-2 ORF8, Unnoticed by Standard Amplicon Sequencing and Variant Calling Pipelines [J].

Brandt, David ;

Simunovic, Marina ;

Busche, Tobias ;

Haak, Markus ;

Belmann, Peter ;

Juenemann, Sebastian ;

Schulz, Tizian ;

Klages, Levin Joe ;

Vinke, Svenja ;

Beckstette, Michael ;

Pohl, Ehmke ;

Scherer, Christiane ;

Sczyrba, Alexander ;

Kalinowski, Joern .

VIRUSES-BASEL, 2021, 13 (09)

[5] Ultrafast Approximation for Phylogenetic Bootstrap [J].

Bui Quang Minh ;

Minh Anh Thi Nguyen ;

von Haeseler, Arndt .

MOLECULAR BIOLOGY AND EVOLUTION, 2013, 30 (05) :1188-1195

[6] BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection [J].

Cao, Yunlong ;

Yisimayi, Ayijiang ;

Jian, Fanchong ;

Song, Weiliang ;

Xiao, Tianhe ;

Wang, Lei ;

Du, Shuo ;

Wang, Jing ;

Li, Qianqian ;

Chen, Xiaosu ;

Yu, Yuanling ;

Wang, Peng ;

Zhang, Zhiying ;

Liu, Pulan ;

An, Ran ;

Hao, Xiaohua ;

Wang, Yao ;

Feng, Rui ;

Sun, Haiyan ;

Zhao, Lijuan ;

Zhang, Wen ;

Zhao, Dong ;

Zheng, Jiang ;

Yu, Lingling ;

Li, Can ;

Zhang, Na ;

Wang, Rui ;

Niu, Xiao ;

Yang, Sijie ;

Song, Xuetao ;

Chai, Yangyang ;

Hu, Ye ;

Shi, Yansong ;

Zheng, Linlin ;

Li, Zhiqiang ;

Gu, Qingqing ;

Shao, Fei ;

Huang, Weijin ;

Jin, Ronghua ;

Shen, Zhongyang ;

Wang, Youchun ;

Wang, Xiangxi ;

Xiao, Junyu ;

Xie, Xiaoliang Sunney .

NATURE, 2022, 608 (7923) :593-+

[7] First detection of SARS-CoV-2 variant B.1.1.529 (Omicron) in Ecuador [J].

Carrazco-Montalvo, A. ;

Armendariz-Castillo, I. ;

Tello, C. L. ;

Morales, D. ;

Armas-Gonzalez, R. ;

Guizado-Herrera, D. ;

Leon-Sosa, A. ;

Ramos-Sarmiento, D. ;

Fuertes, B. ;

Cardenas, P. ;

Marquez, S. ;

Prado-Vivar, B. ;

Guadalupe, J. J. ;

Gutierrez, B. ;

Grunauer, M. ;

Trueba, G. ;

Rojas-Silva, P. ;

Patino, V. Barragan L. .

NEW MICROBES AND NEW INFECTIONS, 2022, 45

[8] Omicron BA.2 (B.1.1.529.2): High Potential for Becoming the Next Dominant Variant [J].

Chen, Jiahui ;

Wei, Guo-Wei .

JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2022, 13 (17) :3840-3849

[9] Serum neutralisation of the SARS-CoV-2 omicron sublineage BA.2 [J].

Chen, Lin-Lei ;

Chu, Allen Wing-Ho ;

Zhang, Ricky Rui-Qi ;

Hung, Ivan Fan-Ngai ;

To, Kelvin Kai-Wang .

LANCET MICROBE, 2022, 3 (06) :E404-E404

[10] UFBoot2: Improving the Ultrafast Bootstrap Approximation [J].

Diep Thi Hoang ;

Chernomor, Olga ;

von Haeseler, Arndt ;

Minh, Bui Quang ;

Le Sy Vinh .

MOLECULAR BIOLOGY AND EVOLUTION, 2018, 35 (02) :518-522

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