Immunological basis that supports the treatment of Multi-System Inflammatory Syndrome in Children (MIS-C/PIMS).

被引:0
作者
Toledo-Salinas, Carla [1 ]
Castano-Jaramillo, Lina Maria [2 ]
Gutierrez-Hernandez, Alonso [3 ]
Scheffler-Mendoza, Selma Cecilia [3 ]
机构
[1] Comis Coordinadora Inst Nacl Salud & Hosp Alta Es, Ciudad de Mexico, Mexico
[2] Fdn Hosp Pediat La Misericordia, Bogota, Colombia
[3] Inst Nacl Pediat, Serv Inmunol Clin, Ciudad de Mexico, Mexico
来源
ACTA PEDIATRICA DE MEXICO | 2023年 / 44卷 / 02期
关键词
COVID-19; immunomodulatory therapy; immunology; Kawasaki-disease; SARS-CoV2; Multi-system inflammatory Syndrome in Children; KAWASAKI-DISEASE; DIAGNOSIS;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Pediatric inflammatory multisystemic syndrome temporarily associated with CO -VID-19 (MIS-C/PIMS) is a new post-infectious condition, secondary to SARS-CoV2 infection. It has been characterized by an inflammatory response with multisystem involvement, involving several mechanisms of immune damage such as an exaggerated increase in cytokines and epithelial damage. Immunomodulatory treatment is aimed at controlling the manifestations of hyperinflammation, to stabilize and prevent long-term sequelae.
引用
收藏
页码:146 / 160
页数:15
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