miR-124-3p mediates polygenic risk shared between schizophrenia and bipolar disorder

被引：4

作者：

Zurawek, Dariusz ^{[1
]}

Turecki, Gustavo ^{[1
]}

机构：

[1] McGill Univ, Douglas Inst, Dept Psychiat, 6875 LaSalle Blvd, Montreal, PQ H4H 1R3, Canada

来源：

NEURON | 2023年 / 111卷 / 02期

关键词：

MICRORNAS;

D O I：

10.1016/j.neuron.2022.12.024

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this issue of Neuron, Namkung et al. demonstrate that the microRNA miR-124-3p is associated with poly-genic risk scores shared between schizophrenia and bipolar disorder and confers risk to behavioral alterations common to these two disorders through modulation of AMPA receptor neurotransmission.

引用

页码：144 / 146

页数：3

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