Role of exosomes in prostate cancer and male fertility

被引：5

作者：

Dey, Dwaipayan ^{[1
]}

Ghosh, Srestha ^{[2
]}

Mirgh, Divya ^{[3
]}

Panda, Siva Parsad ^{[4
]}

Jha, Niraj Kumar ^{[5
,6
,7
]}

Jha, Saurabh Kumar ^{[5
,8
,9
]}

机构：

[1] Ramakrishna Mission Vivekananda Centenary Coll, Dept Microbiol, Rahara 700118, West Bengal, India

[2] Lady Brabourne Coll, Dept Microbiol, Kolkata 700017, West Bengal, India

[3] Johns Hopkins Univ, Baltimore, MD 21218 USA

[4] GLA Univ, Inst Pharmaceut Res, Mathura 281406, Uttar Pradesh, India

[5] Sharda Univ, Sch Engn & Technol, Dept Biotechnol, Greater Noida 201310, India

[6] Lovely Profess Univ, Sch Bioengn & Biosci, Phagwara 144411, India

[7] Chandigarh Univ, Dept Biotechnol Engn & Food Technol, Mohali 140413, India

[8] Saveetha Univ, Saveetha Med Coll & Hosp, Saveetha Inst Med & Tech Sci, Ctr Global Hlth Res, Chennai, India

[9] Uttaranchal Univ, Sch Appl & Life Sci SALS, Dept Biotechnol, Dehra Dun, India

来源：

DRUG DISCOVERY TODAY | 2023年 / 28卷 / 11期

关键词：

exosomes; prostate cancer; metastasis; seminal exosomes; therapeutic; TUMOR-DERIVED EXOSOMES; ANHYDRASE IX EXPRESSION; DRUG-RESISTANCE; MICRORNAS; CELLS; VESICLES; MIRNAS; TECHNOLOGIES; PROGRESSION; METASTASIS;

D O I：

10.1016/j.drudis.2023.103791

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Prostate cancer (PCa) is the second most common and fifth most aggressive neoplasm among men worldwide. In the last decade, extracellular vesicle (EV) research has decoded multiple unsolved cancer-related mysteries. EVs can be classified as microvesicles, apoptotic bodies, and exosomes, among others. Exosomes play a key role in cellular signaling. Their internal cargos (nucleic acids, proteins, lipids) influence the recipient cell. In PCa, the exosome is the regulator of cancer progression. It is also a promising theranostics tool for PCa. Moreover, exosomes have strong participation in male fertility complications. This review aims to highlight the exosome theranostics signature in PCa and its association with male fertility.

引用

页数：10

共 50 条

[1] Role of Exosomes in Prostate Cancer Metastasis
Akoto, Theresa
Saini, Sharanjot
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (07)
[2] Exosomes: The protagonists in the tale of colorectal cancer?
Nabariya, Deepti Kailash
Pallu, Reddanna
Yenuganti, Vengala Rao
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2020, 1874 (02):
[3] The Role of Exosomes in Pancreatic Cancer
Lan, Bin
Zeng, Siyuan
Gruetzmann, Robert
Pilarsky, Christian
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (18)
[4] Role and correlation of exosomes and integrins in bone metastasis of prostate cancer
Geng, Xinyu
Chang, Baoyuan
Shan, Jiahao
ANDROLOGIA, 2022, 54 (10)
[5] Exosomes in Prostate Cancer Diagnosis, Prognosis and Therapy
Lorenc, Tomasz
Klimczyk, Katarzyna
Michalczewska, Izabela
Slomka, Monika
Kubiak-Tomaszewska, Grazyna
Olejarz, Wioletta
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (06) : 1 - 14
[6] Role of exosomes in prostate cancer bone metastasis
Lv, Tingting
Li, Zijie
Wang, Dehua
Guo, Xiaojin
Zhang, Xiaokuan
Cao, Jing
Wang, Zhiyu
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2023, 748
[7] The Role of Tumor Stem Cell Exosomes in Cancer Invasion and Metastasis
Liu, Kun
Gao, Xin
Kang, Baoqiang
Liu, Yunpeng
Wang, Dingding
Wang, Yi
FRONTIERS IN ONCOLOGY, 2022, 12
[8] Role of exosomes in pancreatic cancer (Review)
Yan, Yunmeng
Fu, Guangzhen
Ming, Liang
ONCOLOGY LETTERS, 2018, 15 (05) : 7479 - 7488
[9] The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications
Sundararajan, Vignesh
Sarkar, Fazlul H.
Ramasamy, Thamil Selvee
CELLULAR ONCOLOGY, 2018, 41 (03) : 223 - 252
[10] The role of exosomes on colorectal cancer: A review
Ruiz-Lopez, Lidia
Blancas, Isabel
Garrido, Jose M.
Mut-Salud, Nuria
Moya-Jodar, Marta
Osuna, Antonio
Rodriguez-Serrano, Fernando
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2018, 33 (04) : 792 - 799

← 1 2 3 4 5 →