Distal Chronic Inflammatory Demyelinating Polyneuropathy Following COVID-19 Vaccination in a Patient with Solitary Plasmacytoma: A Case Report and Literature Review

被引：4

作者：

Kubota, Takafumi ^{[1
]}

Shijo, Tomomi ^{[1
]}

Ikeda, Kensho ^{[1
]}

Mitobe, Yoshihiko ^{[1
]}

Umezawa, Shu ^{[1
]}

Misu, Tatsuro ^{[1
]}

Hasegawa, Takafumi ^{[1
]}

Aoki, Masashi ^{[1
]}

机构：

[1] Tohoku Univ, Dept Neurol, Grad Sch Med, Sendai, Japan

来源：

INTERNAL MEDICINE | 2023年 / 62卷 / 16期

关键词：

COVID-19; vaccination; CIDP; anti-ganglioside antibody; myeloma; plasmacytoma; GUILLAIN-BARRE-SYNDROME; DIAGNOSIS; MYELOMA;

D O I：

10.2169/internalmedicine.1365-22

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein report a rare case of distal chronic inflammatory demyelinating polyneuropathy (CIDP) follow-ing coronavirus disease 2019 (COVID-19) vaccination. A 39-year-old woman with a solitary plasmacytoma developed general weakness 7 days after receiving the second dose of the Pfizer-BioNTech COVID-19 vac-cine, which had progressed for 3 months. A neurological examination revealed limb weakness with areflexia. Serological tests identified the presence of IgG antibodies against anti-GM1 and anti-GM2 gangliosides. Comprehensive evaluations met the criteria of distal CIDP. Intravenous immunoglobulin, intravenous methyl-prednisolone, oral prednisolone, and plasma exchange were administered, and she gradually improved. Physi-cians should be aware of CIDP as a rare complication of COVID-19 vaccination.

引用

页码：2419 / 2425

页数：7

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