Distal Chronic Inflammatory Demyelinating Polyneuropathy Following COVID-19 Vaccination in a Patient with Solitary Plasmacytoma: A Case Report and Literature Review

被引:4
作者
Kubota, Takafumi [1 ]
Shijo, Tomomi [1 ]
Ikeda, Kensho [1 ]
Mitobe, Yoshihiko [1 ]
Umezawa, Shu [1 ]
Misu, Tatsuro [1 ]
Hasegawa, Takafumi [1 ]
Aoki, Masashi [1 ]
机构
[1] Tohoku Univ, Dept Neurol, Grad Sch Med, Sendai, Japan
关键词
COVID-19; vaccination; CIDP; anti-ganglioside antibody; myeloma; plasmacytoma; GUILLAIN-BARRE-SYNDROME; DIAGNOSIS; MYELOMA;
D O I
10.2169/internalmedicine.1365-22
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We herein report a rare case of distal chronic inflammatory demyelinating polyneuropathy (CIDP) follow-ing coronavirus disease 2019 (COVID-19) vaccination. A 39-year-old woman with a solitary plasmacytoma developed general weakness 7 days after receiving the second dose of the Pfizer-BioNTech COVID-19 vac-cine, which had progressed for 3 months. A neurological examination revealed limb weakness with areflexia. Serological tests identified the presence of IgG antibodies against anti-GM1 and anti-GM2 gangliosides. Comprehensive evaluations met the criteria of distal CIDP. Intravenous immunoglobulin, intravenous methyl-prednisolone, oral prednisolone, and plasma exchange were administered, and she gradually improved. Physi-cians should be aware of CIDP as a rare complication of COVID-19 vaccination.
引用
收藏
页码:2419 / 2425
页数:7
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