Breaking bad

被引：1

作者：

Bhattacharya, Mohini ^{[1
]}

Horswill, Alexander R. ^{[1
,2
]}

机构：

[1] Univ Colorado, Sch Med, Dept Immunol & Microbiol, Aurora, CO 80045 USA

[2] Eastern Colorado Hlth Care Syst, Dept Vet Affairs, Aurora, CO 80045 USA

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2023年 / 220卷 / 06期

关键词：

D O I：

10.1084/jem.20230421

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

DNASE1 (D1) and DNASE1L3 (D1L3) synergistically reduce the severity of systemic infections caused by Staphylococcus aureus. In this issue of JEM, Lacey et al. developed D1(-/-), D1L3(-/-), and D1(-/-)D1L3(-/-) mice to show that exogenous addition of the DNase formulation Dornase alfa could facilitate removal of biofilms.

引用

页数：3

共 13 条

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