Post-discharge use of antipsychotics in patients with hospital-acquired delirium and associated risk of mortality-A population-based nested case-control study

被引：3

作者：

Tsai, Daniel Hsiang-Te ^{[1
,2
]}

Chang, Wei-Hung ^{[3
,4
,5
]}

Lin, Hsiang-Wen ^{[6
,7
,8
,9
]}

Lin, Swu-Jane ^{[9
]}

Shao, Shih-Chieh ^{[1
,10
]}

Lai, Edward Chia-Cheng ^{[1
]}

机构：

[1] Natl Cheng Kung Univ, Inst Clin Pharm & Pharmaceut Sci, Coll Med, Sch Pharm, Tainan, Taiwan

[2] St Georges Univ London, Ctr Neonatal & Paediat Infect, London, England

[3] Natl Cheng Kung Univ, Natl Cheng Kung Univ Hosp, Coll Med, Dept Psychiat, Tainan, Taiwan

[4] Natl Cheng Kung Univ Hosp, Dept Psychiat, Dou Liou Branch, Yunlin, Taiwan

[5] Natl Cheng Kung Univ, Inst Clin Med, Coll Med, Tainan, Taiwan

[6] China Med Univ, Coll Pharm, Sch Pharm, Taichung, Taiwan

[7] China Med Univ, Grad Inst, Coll Pharm, Taichung, Taiwan

[8] China Med Univ Hosp, Dept Pharm, Taichung, Taiwan

[9] Univ Illinois, Coll Pharm, Dept Pharm Syst Outcomes & Policy, Chicago, IL USA

[10] Keelung Chang Gung Mem Hosp, Dept Pharm, Keelung, Taiwan

来源：

ASIAN JOURNAL OF PSYCHIATRY | 2023年 / 83卷

关键词：

Hospital-acquired delirium; Antipsychotics; Mortality; Haloperidol; Risperidone; INSURANCE RESEARCH DATABASE; ADULTS; CARE;

D O I：

10.1016/j.ajp.2023.103533

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: To evaluate post-discharge use of antipsychotics in patients with incident hospital-acquired delirium and the associated risk of mortality.Methods: We conducted a nested case-control study for patients newly diagnosed with hospital-acquired delirium and subsequently discharged from hospital using Taiwan's National Health Insurance Database (NHID) from 2011 to 2018.Results: The use of antipsychotics after discharge did not increase the risk of mortality (adjusted OR: 1.03; 95% CI: 0.98-1.09).Conclusions: The findings suggested that using antipsychotics after discharge in patients with hospital-acquired delirium may not increase the risk of mortality.

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页数：4

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