Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications

被引：58
作者：
Hama, Rikako [1 ,2 ]
Ulziibayar, Anudari [1 ]
Reinhardt, James W. [1 ]
Watanabe, Tatsuya [1 ]
Kelly, John [1 ]
Shinoka, Toshiharu [1 ,3 ,4 ]
机构：
[1] Nationwide Childrens Hosp, Abigail Wexner Res Inst, Ctr Regenerat Med, 700 Childrens Dr, Columbus, OH 43205 USA
[2] Tokyo Univ Agr & Technol, Grad Sch Engn, Dept Biotechnol & Life Sci, 2-24-16 Naka Cho, Koganei 1848588, Japan
[3] Nationwide Childrens Hosp, Heart Ctr, Dept Cardiothorac Surg, 700 Childrens Dr, Columbus, OH 43205 USA
[4] Ohio State Univ, Dept Surg, Cardiovasc Tissue Engn Program, Columbus, OH 43210 USA
来源：
BIOMOLECULES | 2023年 / 13卷 / 02期
关键词：
tissue engineering; hydrogel; drug delivery system (DDS); biodegradation; silk fibroin; collagen; elastin; chitosan; proteoglycan; METHACRYLOYL GELMA HYDROGELS; IN-VITRO CHARACTERIZATION; CROSS-LINKING; MECHANICAL-PROPERTIES; CONTROLLED-RELEASE; SKIN REGENERATION; GELATIN; CHITOSAN; COLLAGEN; FIBRIN;
D O I：
10.3390/biom13020280
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Hydrogels are being investigated for their application in inducing the regeneration of various tissues, and suitable conditions for each tissue are becoming more apparent. Conditions such as the mechanical properties, degradation period, degradation mechanism, and cell affinity can be tailored by changing the molecular structure, especially in the case of polymers. Furthermore, many high-functional hydrogels with drug delivery systems (DDSs), in which drugs or bioactive substances are contained in controlled hydrogels, have been reported. This review focuses on the molecular design and function of biopolymer-based hydrogels and introduces recent developments in functional hydrogels for clinical applications.
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页数：16
相关论文
共 95 条
[1]   Fibrin: A versatile scaffold for tissue engineering applications [J].
Ahmed, Tamer A. E. ;
Dare, Emma V. ;
Hincke, Max .
TISSUE ENGINEERING PART B-REVIEWS, 2008, 14 (02) :199-215
[2]   Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications [J].
Alves, N. M. ;
Mano, J. F. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2008, 43 (05) :401-414
[3]   Advanced Silk Fibroin Biomaterials and Application to Small-Diameter Silk Vascular Grafts [J].
Asakura, Tetsuo ;
Tanaka, Takashi ;
Tanaka, Ryo .
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2019, 5 (11) :5561-5577
[4]   Influence of the degree of methacrylation on hyaluronic acid hydrogels properties [J].
Bencherif, Sidi A. ;
Srinivasan, Abiraman ;
Horkay, Ferenc ;
Hollinger, Jeffrey O. ;
Matyjaszewski, Krzysztof ;
Washburn, Newell R. .
BIOMATERIALS, 2008, 29 (12) :1739-1749
[5]  
Bliley JM, 2015, STEM CELL BIOLOGY AND TISSUE ENGINEERING IN DENTAL SCIENCES, P149, DOI 10.1016/B978-0-12-397157-9.00013-8
[6]   Mechanically Robust and Bioadhesive Collagen and Photocrosslinkable Hyaluronic Acid Semi-Interpenetrating Networks [J].
Brigham, Mark D. ;
Bick, Alexander ;
Lo, Edward ;
Bendali, Amel ;
Burdick, Jason A. ;
Khademhosseini, Ali .
TISSUE ENGINEERING PART A, 2009, 15 (07) :1645-1653
[7]   Biomedical applications of hydrogels: A review of patents and commercial products [J].
Calo, Enrica ;
Khutoryanskiy, Vitaliy V. .
EUROPEAN POLYMER JOURNAL, 2015, 65 :252-267
[8]   Overview of natural hydrogels for regenerative medicine applications [J].
Catoira, Marta Calvo ;
Fusaro, Luca ;
Di Francesco, Dalila ;
Ramella, Martina ;
Boccafoschi, Francesca .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2019, 30 (10)
[9]   Chitosan/POSS Hybrid Hydrogels for Bone Tissue Engineering [J].
Celesti, Consuelo ;
Iannazzo, Daniela ;
Espro, Claudia ;
Visco, Annamaria ;
Legnani, Laura ;
Veltri, Lucia ;
Visalli, Giuseppa ;
Di Pietro, Angela ;
Bottino, Paola ;
Chiacchio, Maria Assunta .
MATERIALS, 2022, 15 (22)
[10]   4D Printing of Hydrogels: A Review [J].
Champeau, Mathilde ;
Heinze, Daniel Alves ;
Viana, Thiago Nunes ;
de Souza, Edcarlos Rodrigues ;
Chinellato, Anne Cristine ;
Titotto, Silvia .
ADVANCED FUNCTIONAL MATERIALS, 2020, 30 (31)
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