Die Varikose, das Krampfaderleiden, stellt ein haufiges Krankheitsbild dar. Die Kompressionstherapie kommt hier standardma ss ig zur Anwendung. Bei der Psoriasis vulgaris, einer chronisch-entzundlichen Hauterkrankung, konnen lokale Reize das Auftreten typischer Hautlasionen triggern. Ein ortlicher Zusammenhang psoriatischer Plaques und Varizen wird klinisch beobachtet. Im dargestellten Fall verhalf eine erganzende Kompression zur Abheilung. Abstract In Germany, about 25% of the population show signs of chronic venous insufficiency (CVI). Pathophysiologically, varicosis is based on a weakness of the vein wall, which can be attributed to a decrease in elastic fibres and muscle cells. The main indications for medical compression therapy are chronic and thromboembolic venous diseases and oedema. The effect of this therapy relies on different mechanisms, which lead to reduction in venous hypertension by reducing the venous vessel cross-section, promoting the venous return and activating the calf muscle pump. It is clinically known that, in addition to external so-called exogenous stimuli, internal (endogenous) factors such as varicosis can also "trigger" dermatoses such as the psoriasis present in the case study. In refractory psoriatic lesions of the lower extremities, a detailed history, clinical examination, and colour-coded duplex sonography should be performed to diagnose relevant concomitant venous diseases. Depending on the findings, additional compression therapy can be considered and, if necessary, further phlebological therapy can be initiated. Prospective studies should be planned to investigate the clinical impression and the pathophysiological relationship between therapy-resistant skin changes and varicosis.