Impedance Analysis on Interaction Between Ofloxacin and Supported Bilayer Lipid Membrane(BLM)

被引:0
|
作者
Poornima, K. [1 ]
Sankar, A. [2 ]
Rameshkumar, S.
Periasamy, M. [3 ]
机构
[1] Govt Coll Engn, Dept Chem, Salem 11, Tamil Nadu, India
[2] Kandaswami Kandars Coll, Dept Chem, Namakkal, Tamil Nadu, India
[3] Thiruvallur Govt Arts Coll, Dept Chem, Namakkal, Tamil Nadu, India
关键词
Bilayer lipid membrane; Ofloxacin; EIS; Biomembrane; NaCl bath; PHOSPHATIDYLCHOLINE; STABILITY;
D O I
10.13005/ojc/390426
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Using the EIS method (Electrochemical Impedance Spectroscopy), the interaction of the (Bilayer Lipid Membrane) BLM system with Ofloxacin in NaCl bath solutions was studied. The BLM system shows electrical properties and stability, which mainly depend on the concentration of the sodium chloride bath solution. The stability of the BLM system increased due to the increase in the concentration of NaCl. On the surface of BLM, a fixing impact has been created due to the cations. The Ofloxacin atoms get divided into the BLM stage and display the fluidization impact. The resistance of the membrane decreases with the concentration of Ofloxacin. To identify Ofloxacin in the arrangement, an impedimetric sensor was created. The level of Ofloxacin detected mainly depends on the sodium chloride concentration present in the bath solution.
引用
收藏
页码:1007 / 1014
页数:8
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