Myelin oligodendrocyte glycoprotein antibody-associated disease presenting with dystonia

被引：0

作者：

Zveik, Omri ^{[1
,2
,3
]}

Berman, Tal Benoliel ^{[1
,2
,3
]}

Keadan, Tarek ^{[1
,2
,3
]}

Barhum, Khalil ^{[1
,4
]}

Rechtman, Ariel ^{[1
,2
,3
]}

Vaknin-Dembinsky, Adi ^{[1
,2
,3
,5
]}

机构：

[1] Hebrew Univ Jerusalem, Fac Med, Jerusalem, Israel

[2] Hadassah Hebrew Univ, Agnes Ginges Ctr Human Neurogenet, Dept Neurol, Med Ctr, Jerusalem, Israel

[3] Hadassah Hebrew Univ, Agnes Ginges Ctr Human Neurogenet, Lab Neuroimmunol, Med Ctr, Jerusalem, Israel

[4] Hadassah Hebrew Univ, Dept Radiol, Med Ctr, Jerusalem, Israel

[5] Hadassah Med Ctr, Neurol Dept, Multiple Sclerosis & Immunobiol Res, POB 12000, IL-91120 Jerusalem, Israel

来源：

NEUROLOGY AND CLINICAL NEUROSCIENCE | 2024年 / 12卷 / 01期

关键词：

dystonia; MOG; MOGAD; Myelin oligodendrocyte glycoprotein antibody-associated disease;

D O I：

10.1111/ncn3.12775

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) commonly presents as optic neuritis or transverse myelitis. We report an atypical clinical presentation for MOGAD in a 28-year-old female experiencing right-arm dystonic episodes. MRI scans demonstrated multifocal periventricular and subcortical lesions, including in the left centrum semiovale and corona radiata. Despite the atypical presentation, her clinical, serological, and radiographic features favor a MOGAD diagnosis. This report emphasizes the heterogeneity of MOGAD phenotypes and the need to consider MOGAD, even in a non-typical presentation.

引用

页码：65 / 67

页数：3

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