The role of coenzyme Q10 as a preventive and therapeutic agent for the treatment of cancers

被引：10
作者：
Dabaghi, Ghazal Ghasempour [1 ]
Rad, Mehrdad Rabiee [1 ]
Mohammad-Zamani, Mahtab [1 ]
Shervedani, Atieh Karimi [1 ]
Bahrami-Samani, Farnaz [1 ]
Heshmat-Ghahdarijani, Kiyan [2 ]
机构：
[1] Isfahan Univ Med Sci, Sch Med, Esfahan, Iran
[2] Isfahan Univ Med Sci, Cardiovasc Res Inst, Heart Failure Res Ctr, Shahid Rahmani Alley,Moshtagh Sevom St, Esfahan, Iran
来源：
CURRENT PROBLEMS IN CANCER | 2024年 / 48卷
关键词：
Cancer; Coenzyme Q10; Dietary supplementation; Neoplasm; Prevention; Ubiquinone; CERVICAL INTRAEPITHELIAL NEOPLASIA; BREAST-CANCER; PROSTATE-CANCER; LUNG-CANCER; Q(10) LEVELS; HEPATOCELLULAR-CARCINOMA; OXIDATIVE STRESS; UP-REGULATION; DOUBLE-BLIND; L-CARNITINE;
D O I：
10.1016/j.currproblcancer.2024.101063
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Currently, several options are available for the prevention and treatment of cancers; however, many limitations remain with these approaches. Recently, antioxidants have become important preventive and therapeutic alternatives with few adverse events and minimum cost. Coenzyme Q10 (CoQ10) is a naturally occurring component that performs an anticancer function by reducing oxidative stress. CoQ10 supplementation as an adjuvant therapy offers more progress in the elimination and development of cancers. This review aimed to critically assess and summarize the implication of CoQ10 in cancers, highlighting possible mechanisms, and future directions of research for the standardization of the current regimen for cancer prevention and treatment.
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页数：9
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