Pd-catalyzed vinyl C-H amination with diaziridinone

被引：2

作者：

Wang, Jianjun ^{[1
]}

Hong, Huiying ^{[1
]}

Hu, Daguo ^{[1
]}

Liu, Jieling ^{[1
]}

Liu, Wei ^{[1
]}

Shi, Yian ^{[1
]}

机构：

[1] Changzhou Univ, Inst Nat & Synthet Organ Chem, Changzhou 213164, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2024年 / 11卷 / 02期

基金：

中国国家自然科学基金;

关键词：

N BOND FORMATION; ENAMIDES; INDOLES; 2-VINYLANILINES; MYXOBACTERIA; HETEROCYCLES; DERIVATIVES; CARBAZOLES; MACROLIDES; ARYLATION;

D O I：

10.1039/d3qo01472j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This work describes a Pd-catalyzed vinyl C-H amination of N-(quinolin-8-yl)acrylamides with di-t-butyldiaziridinone, providing ready access to a variety of 3-amino-N-(quinolin-8-yl)acrylamides. The reaction likely proceeds via vinyl C-H activation to form a pallada(ii)cycle and subsequent amination with di-t-butyldiaziridinone. 3-Amino-N-(quinolin-8-yl)acrylamides are obtained with up to 78% yield via Pd-catalyzed vinyl C-H amination with di-tert-butyldiaziridinone as a nitrogen source.

引用

页码：484 / 488

页数：5

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