Biological therapy of severe asthma- Position of Polish Society of Allergology and Polish Society of Respiratory Diseases

被引:1
作者
Rogala, Barbara [1 ,9 ]
Kupczyk, Maciej [2 ]
Bochenek, Grazyna [3 ]
Sliwinski, Pawel [4 ]
Moniuszko, Marcin [5 ]
Kuna, Piotr [2 ]
Gluck, Joanna [1 ]
Dobek, Rafal [4 ]
Kulus, Marek [6 ]
Kucharczyk, Aleksandra [7 ]
Chalubinski, Maciej [8 ]
机构
[1] Slaski Uniwersytet Med Katowicach, Uniwersyteckie Ctr Klin, Katowice, Poland
[2] Uniwersytet Med Lodzi, Klin Chorob Wewnetrznych Astmy & Alergii, Lodz, Poland
[3] Uniwersytet Jagiellonki, Katedra Chorob Wewnetrznych 2, Coll Med Krakowie, Krakow, Poland
[4] Inst Gruzlicy & Chorob Pluc Warszawie, Klin Chorob Pluc, Warsaw, Poland
[5] Uniwersytet Med Bialymstoku, Klin Alergol & Chorob Wewnetrznych, Bialystok, Poland
[6] Warszawski Uniwersytet Med, Klin Pneumonol & Alergol Wieku Dzieciecego, Warsaw, Poland
[7] Wojskowy Inst Med Warszawie, Klin Chorob Wewnetrznych Pneumonol & Alergol, Warsaw, Poland
[8] Uniwersytet Med Lodzi, Klin Immunol & Alergii, Lodz, Poland
[9] Slaski Uniwersytet Med, Uniwersyteckie Ctr Klin, Ul Medykow 14, PL-40752 Katowice, Poland
关键词
severe asthma; immunopathophysiology; biological therapy; efficacy; safety; SEVERE EOSINOPHILIC ASTHMA; TO-SEVERE ASTHMA; DOUBLE-BLIND; OMALIZUMAB; SAFETY; MULTICENTER; MEPOLIZUMAB; BENRALIZUMAB; RISK; REMISSION;
D O I
10.5114/pja.2023.129093
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Biological therapy represents a breakthrough advance in the treatment of many diseases, including asthma. use of biological drugs, the essence of whose mechanism is a suppressive effect on biologically active proteins determining the phenotypic manifestation of the disease. Data demonstrating the safety and efficacy of biological therapy and the prospects for further development of this area of medicine are presented.
引用
收藏
页码:77 / 99
页数:23
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