Effects of endocrine disrupting compounds on female fertility

被引:24
作者
Panagopoulos, Periklis [1 ]
Mavrogianni, Despina [2 ]
Christodoulaki, Chryssi [3 ]
Drakaki, Eirini [2 ]
Chrelias, Georgios [1 ]
Panagiotopoulos, Dimitrios [1 ]
Potiris, Anastasios [1 ]
Drakakis, Peter [1 ,2 ]
Stavros, Sofoklis [1 ]
机构
[1] Natl & Kapodistrian Univ Athens, Univ Hosp ATTIKON, Med Sch, Dept Obstet & Gynecol 3, Athens, Greece
[2] Natl & Kapodistrian Univ Athens, Alexandra Hosp, Med Sch, Dept Obstet & Gynecol 1, Athens, Greece
[3] Chania Gen Hosp St George, Dept Obstet & Gynecol, Mournies, Greece
关键词
Endocrine disrupting compounds (EDCs); Female fertility; Phthalates; Pesticides; Bisphenol A (BPA); Bisphenol S (BPS); BISPHENOL-A; CHEMICALS; EXPOSURE; RESPONSES; HEALTH; DDT;
D O I
10.1016/j.bpobgyn.2023.102347
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Endocrine Disrupting Compounds or Chemicals (EDCs) constitute an extensive and varied group of mostly non-natural chemicals that have the ability to imitate any aspect of hormone action, perturbing many physiological functions in humans and animals. As for female fertility, several EDCs are associated with adverse effects in the regulation of steroidogenesis, higher miscarriage rates as well as lower fertilization and embryo implantation rates and some of them are considered to decrease the number of high-quality embryos in assisted reproductive technology (ART) preg-nancy. The most common EDCs are pesticides, hexachlorobenzene (HCB), hexachlorocyclohexane (HCH) and especially phthalates and bisphenols which are used in thousands of products as plas-ticizers. Among all, Bisphenol A (BPA) is one of the most perme-ating and well-studied EDCs. BPA's action resembles that of estradiol affecting negatively the female reproductive system in various ways. This review summarizes the most recent literature on the impact of EDCs in female fertility.& COPY; 2023 Elsevier Ltd. All rights reserved.
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页数:11
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