Hemoglobin, albumin, lymphocyte, and platelet score as a predictor of prognosis in metastatic gastric cancer

被引：13

作者：

Duzkopru, Yakup ^{[1
,2
]}

Kocanoglu, Abdulkadir ^{[1
]}

Dogan, Ozlem ^{[1
]}

Sahinli, Hayriye ^{[1
]}

Cilbir, Ebru ^{[1
]}

Altinbas, Mustafa ^{[1
]}

机构：

[1] Ankara Etlik City Hosp, Dept Med Oncol, TR-06170 Ankara, Turkiye

[2] Ankara Etlik City Hosp, Dept Med Oncol, Halil Sezai Erkut St, TR-06170 Ankara, Turkiye

来源：

WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY | 2023年 / 15卷 / 09期

关键词：

Biomarker; Hemoglobin; albumin; lymphocyte; and platelet score; Gastric cancer; Nutritional index; Prognosis; Survival; PREOPERATIVE HEMOGLOBIN; IMPACT;

D O I：

10.4251/wjgo.v15.i9.1626

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

BACKGROUND The hemoglobin, albumin, lymphocyte, and platelet (HALP) score, derived from a composite evaluation of markers reflecting the tumor-inflammation relationship and nutritional status, has been substantiated as a noteworthy prognostic determinant for diverse malignancies.AIM To investigate how the HALP score relates to prognosis in patients with metastatic gastric cancer.METHODS The cutoff values for the HALP score, neutrophil/lymphocyte ratio, and platelet/lymphocyte ratio were determined using receiver operating characteristic analysis. Low HALP scores were defined as those less than 24.79 and high HALP scores as those greater than 24.79.RESULTS The study cohort comprised 147 patients and 110 of them (74.8%) were male. The patients' median age was 63 (22-89) years. The median overall survival was significantly superior in the patients with high HALP scores than in those with low HALP scores (10.4 mo vs 7.5 mo, respectively; P < 0.001)CONCLUSION The HALP score was found to be a prognostic factor in patients with metastatic gastric cancer.

引用

页码：1626 / 1635

页数：11

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