18F-FDG-PET/CT for Localizing the Epileptogenic Focus in Patients with Different Types of Focal Cortical Dysplasia

被引：0
作者：
Wang, Feng [1 ]
Hong, Shu-Ting [1 ]
Zhang, Ying [2 ]
Xing, Zhen [3 ]
Lin, Yuan-Xiang [1 ]
机构：
[1] Fujian Med Univ, Affiliated Hosp 1, Neurosurg Dept, Fuzhou, Fujian, Peoples R China
[2] Fujian Med Univ, Affiliated Hosp, Nucl Med Dept, Fuzhou, Fujian, Peoples R China
[3] Fujian Med Univ, Affiliated Hosp 1, Radiol Dept, Fuzhou, Fujian, Peoples R China
来源：
NEUROPSYCHIATRIC DISEASE AND TREATMENT | 2024年 / 20卷
关键词：
focal cortical dysplasia; epilepsy; F-18-FDG-PET/CT; pathological types; FDG-PET; DIAGNOSTIC METHODS; EPILEPSY SURGERY; BRAIN; MRI; CLASSIFICATION; SPECTRUM; UTILITY; TISSUE; CORTEX;
D O I：
10.2147/NDT.S442459
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Purpose: To determine the diagnostic and localization value of F-18-fluorodeoxyglucose-positron emission tomography (PET)/computed tomography (CT) in patients with focal cortical dysplasia (FCD) who underwent epilepsy surgery. Methods: One hundred and eight patients with pathologically proven FCD who underwent surgery for refractory epilepsy were retrospectively analyzed. All patients underwent magnetic resonance imaging (MRI), F-18-FDG-PET/CT, and video electroencephalography. An MRI diagnosis of FCD was defined as MRI+. A PET/CT diagnosis of FCD was defined as PET/CT+. Results: MRI and PET/CT detected FCD in 20.37% and 93.52% of patients, respectively. The difference was significant. Twenty-one patients were MRI+/PET+, 80 were MRI-/PET+, six were MRI-/PET-, and one was MRI+/PET-. The MRI positivity rate was lowest in patients with FCD type IIIa (5.6%, P < 0.05). Prevalence of MRI-/PET+ was highest in patients with FCD type IIIa (88.89%, P < 0.05). Conclusion: PET/CT is superior to MRI in detecting FCD. FCD type IIIa was more likely than other types to show MRI-/PET+. This suggests that PET/CT has particular diagnostic value for FCD type IIIa patients with negative MRI findings
引用
收藏
页码：211 / 220
页数：10
相关论文
共 50 条
[41]   Is 18F-FDG-PET/CT a helpful tool to diagnose PSP clinical variants? [J].
Marti-Andres, G. ;
Riverol-Fernandez, M. ;
Valenti-Azcarate, R. ;
Fernandez-Matarrubia, M. ;
Prieto-Azcarate, E. ;
Arbizu-Azcarate, J. ;
Luquin-Piudo, M. R. .
MOVEMENT DISORDERS, 2019, 34 :S810-S811
[42]   An update on the role of 18F-FDG-PET/CT in major infectious and inflammatory diseases [J].
Kung, Boom Ting ;
Seraj, Siavash Mehdizadeh ;
Zadeh, Mahdi Zirakchian ;
Rojulpote, Chaitanya ;
Kothekar, Esha ;
Ayubcha, Cyrus ;
Ng, Kwok Sing ;
Ng, Koon Kiu ;
Au-Yong, Ting Kun ;
Werner, Thomas J. ;
Zhuang, Hongming ;
Hunt, Stephen J. ;
Hess, Soren ;
Alavi, Abass .
AMERICAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2019, 9 (06) :255-273
[43]   Clitoral Metastasis From Advanced Cervical Carcinoma on 18F-FDG-PET/CT [J].
Lu, Yu-Yu ;
Lu, Chien-Hsing ;
Wang, Hsin-Yi .
CLINICAL NUCLEAR MEDICINE, 2017, 42 (01) :54-55
[44]   18F-FDG-PET/CT in a patient with suspected recurrence of germ cell tumor [J].
Penna, Daniele ;
Arena, Vincenzo ;
Pelosi, Ettore .
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2013, 9 (03) :520-522
[45]   Prospective evaluation of CECT and 18F-FDG-PET/CT in detection of hepatic metastases [J].
D'Souza, Maria Mathew ;
Sharma, Rajnish ;
Mondal, Anupam ;
Jaimini, Abhinav ;
Tripathi, Madhavi ;
Saw, Sanjiv Kumar ;
Singh, Dinesh ;
Mishra, Anil ;
Tripathi, Rajendra Prasad .
NUCLEAR MEDICINE COMMUNICATIONS, 2009, 30 (02) :117-125
[46]   A comparison of the diagnostic value of MRI and 18F-FDG-PET/CT in suspected spondylodiscitis [J].
Carolijn Smids ;
Ilse J. E. Kouijzer ;
Fidel J. Vos ;
Tom Sprong ;
Allard J. F. Hosman ;
Jacky W. J. de Rooy ;
Erik H. J. G. Aarntzen ;
Lioe-Fee de Geus-Oei ;
Wim J. G. Oyen ;
Chantal P. Bleeker-Rovers .
Infection, 2017, 45 :41-49
[47]   A comparison of the diagnostic value of MRI and 18F-FDG-PET/CT in suspected spondylodiscitis [J].
Smids, Carolijn ;
Kouijzer, Ilse J. E. ;
Vos, Fidel J. ;
Sprong, Tom ;
Hosman, Allard J. F. ;
de Rooy, Jacky W. J. ;
Aarntzen, Erik H. J. G. ;
de Geus-Oei, Lioe-Fee ;
Oyen, Wim J. G. ;
Bleeker-Rovers, Chantal P. .
INFECTION, 2017, 45 (01) :41-49
[48]   18F-FDG PET in drug-resistant epilepsy due to focal cortical dysplasia type 2: additional value of electroclinical data and coregistration with MRI [J].
Serge Desarnaud ;
Charles Mellerio ;
Franck Semah ;
Agathe Laurent ;
Elisabeth Landre ;
Bertrand Devaux ;
Catherine Chiron ;
Vincent Lebon ;
Francine Chassoux .
European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45 :1449-1460
[49]   Diagnostic role of 18F-FDG-PET or PET/CT in salivary gland tumors: A systematic review [J].
Bertagna, F. ;
Nicolai, P. ;
Maroldi, R. ;
Mattavelli, D. ;
Bertoli, M. ;
Giubbini, R. ;
Lombardi, D. ;
Treglia, G. .
REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR, 2015, 34 (05) :295-302
[50]   Characterisation of a novel [18F]FDG brain PET database and combination with a second database for optimising detection of focal abnormalities, using focal cortical dysplasia as an example [J].
Jin, Sameer Omer ;
Merida, Ines ;
Stavropoulos, Ioannis ;
Elwes, Robert D. C. ;
Lam, Tanya ;
Guedj, Eric ;
Girard, Nadine ;
Costes, Nicolas ;
Hammers, Alexander .
EJNMMI RESEARCH, 2023, 13 (01)
12345