18F-FDG-PET/CT for Localizing the Epileptogenic Focus in Patients with Different Types of Focal Cortical Dysplasia

被引：0
作者：
Wang, Feng [1 ]
Hong, Shu-Ting [1 ]
Zhang, Ying [2 ]
Xing, Zhen [3 ]
Lin, Yuan-Xiang [1 ]
机构：
[1] Fujian Med Univ, Affiliated Hosp 1, Neurosurg Dept, Fuzhou, Fujian, Peoples R China
[2] Fujian Med Univ, Affiliated Hosp, Nucl Med Dept, Fuzhou, Fujian, Peoples R China
[3] Fujian Med Univ, Affiliated Hosp 1, Radiol Dept, Fuzhou, Fujian, Peoples R China
来源：
NEUROPSYCHIATRIC DISEASE AND TREATMENT | 2024年 / 20卷
关键词：
focal cortical dysplasia; epilepsy; F-18-FDG-PET/CT; pathological types; FDG-PET; DIAGNOSTIC METHODS; EPILEPSY SURGERY; BRAIN; MRI; CLASSIFICATION; SPECTRUM; UTILITY; TISSUE; CORTEX;
D O I：
10.2147/NDT.S442459
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Purpose: To determine the diagnostic and localization value of F-18-fluorodeoxyglucose-positron emission tomography (PET)/computed tomography (CT) in patients with focal cortical dysplasia (FCD) who underwent epilepsy surgery. Methods: One hundred and eight patients with pathologically proven FCD who underwent surgery for refractory epilepsy were retrospectively analyzed. All patients underwent magnetic resonance imaging (MRI), F-18-FDG-PET/CT, and video electroencephalography. An MRI diagnosis of FCD was defined as MRI+. A PET/CT diagnosis of FCD was defined as PET/CT+. Results: MRI and PET/CT detected FCD in 20.37% and 93.52% of patients, respectively. The difference was significant. Twenty-one patients were MRI+/PET+, 80 were MRI-/PET+, six were MRI-/PET-, and one was MRI+/PET-. The MRI positivity rate was lowest in patients with FCD type IIIa (5.6%, P < 0.05). Prevalence of MRI-/PET+ was highest in patients with FCD type IIIa (88.89%, P < 0.05). Conclusion: PET/CT is superior to MRI in detecting FCD. FCD type IIIa was more likely than other types to show MRI-/PET+. This suggests that PET/CT has particular diagnostic value for FCD type IIIa patients with negative MRI findings
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页码：211 / 220
页数：10
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