Label-Free Optical Fiber Glucose Biosensor Based on Two-Mode Interference

被引：4

作者：

Cheng, Tonglei ^{[1
,2
]}

Sun, Yuanqi ^{[1
]}

Yan, Xin ^{[1
]}

Zhang, Xuenan ^{[1
]}

Wang, Fang ^{[1
]}

Zhou, Xue ^{[1
]}

机构：

[1] Northeastern Univ, Coll Informat Sci & Engn, State Key Lab Synthet Automat Proc Ind, Shenyang 110819, Peoples R China

[2] Hebei Key Lab Micro Nano Precis Opt Sensing & Mea, Qinhuangdao 066004, Hebei, Peoples R China

来源：

IEEE SENSORS JOURNAL | 2023年 / 23卷 / 11期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

Biosensor; glucose; mode interference; refractive index (RI); REFRACTIVE-INDEX; HIGH-SENSITIVITY; SENSOR; INTERFEROMETER; GRAPHENE; COMPOSITE; SERUM;

D O I：

10.1109/JSEN.2023.3266751

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A label-free glucose biosensor has been proposed and demonstrated in this article based on a tapered two-mode fiber (TTMF) sandwiched between two single-mode fibers (SMFs). The tapering technique helps excite the LP11 mode in TTMF, forming uniform interference fringe containing the LP01 and LP11 modes. The experimental results show that the sensor's sensitivity increases, as the TTMF waist diameter decreases, and at the TTMF diameter of 13.12 mu m, the maximum glucose sensitivity can reach 0.112 nm/mg/mL, while the temperature sensitivity is as low as 16.43 pm/degrees C. With compact structure, label-free sensing capacity, and ease fabrication, this proposed biosensor has bright application prospect in the fields of food safety, disease diagnosis, and clinical analysis.

引用

页码：11642 / 11647

页数：6

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