Triple combination targeting PI3K, ER, and CDK4/6 inhibits growth of ER-positive breast cancer resistant to fulvestrant and CDK4/6 or PI3K inhibitor

被引:3
作者
Karimi, Leena [1 ]
Alves, Carla L. [1 ]
Terp, Mikkel G. [1 ]
Tuttolomondo, Martina [1 ]
Portman, Neil [2 ,3 ]
Ehmsen, Sidse [1 ,4 ]
Johansen, Lene E. [1 ]
Bak, Martin [5 ]
Lim, Elgene [2 ,3 ]
Ditzel, Henrik J. [1 ,6 ,7 ]
机构
[1] Univ Southern Denmark, Inst Mol Med, Dept Canc & Inflammat Res, Odense, Denmark
[2] Garvan Inst Med Res, Sydney, NSW, Australia
[3] Univ New South Wales Sydney, Fac Med, St Vincents Clin Sch, Sydney, NSW, Australia
[4] Odense Univ Hosp, Inst Clin Res, Dept Oncol, Odense, Denmark
[5] Sydvestjysk Sygehus, Dept Pathol, Esbjerg, Denmark
[6] Odense Univ Hosp, Acad Geriatr Canc Res AgeCare, Odense, Denmark
[7] Univ Southern Denmark, Inst Mol Med, Dept Canc & Inflammat Res, DK-5000 Odense, Denmark
关键词
PLUS FULVESTRANT; MONARCH; 2; ABEMACICLIB; ALPELISIB;
D O I
10.1002/cac2.12425
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:720 / 725
页数:6
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