Does Gender Affirming Hormone Therapy Increase the Risk of Kidney Disease?

被引：3
作者：
Eckenrode, Han E. [1 ]
Carwie, J. Caroline [2 ]
Curtis, Lisa M. [1 ,3 ]
机构：
[1] Univ Alabama Birmingham, Dept Med, Div Nephrol, Birmingham, AL USA
[2] Univ Georgia, Div Biol Sci, Athens, GA USA
[3] Univ Alabama Birmingham, Div Nephrol, MCLM 531,1918 Univ Blvd, Birmingham, AL 35233 USA
来源：
SEMINARS IN NEPHROLOGY | 2022年 / 42卷 / 03期
基金：
美国国家卫生研究院;
关键词：
Sex differences; acute kidney injury; chronic kidney disease; transgender; SEX-DIFFERENCES; RENAL ISCHEMIA; TRANSGENDER; TESTOSTERONE; PROGRESSION; URINARY; NERVOSA; STATES; CARE;
D O I：
10.1016/j.semnephrol.2022.10.010
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Kidney health and manifestation of disease in transgender men, women, and nonbinary individuals are not well understood. Transgender individuals commonly receive gender-affirming hormone therapy (GAHT) to align their outward appearance with their gender. Recent attention to the differences in fundamental kidney parameters has identified that transgender individuals may manifest levels of these biomarkers differently than their cisgender coun-terparts. Improving understanding of the differences in biomarkers and in the development of kidney disease is essential to providing appropriate kidney care to this vulnerable population. In this review, we introduce the current information related to GAHT and kidney health and highlight the significant gaps in our understanding of how GAHT may affect kidney physiology and pathophysiology. Semin Nephrol 42:151284 (c) 2022 Elsevier Inc. All rights reserved.
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页数：7
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