Adipocytic Differentiation in a Sertoli Cell Tumor

被引:0
作者
Molina, Jordan [1 ]
Dabaja, Ali [2 ]
Gupta, Nilesh [1 ,3 ]
Alruwaii, Fatimah I. [1 ]
Hassan, Oudai [1 ,3 ]
Al-Obaidy, Khaleel I. [1 ,3 ,4 ]
机构
[1] Henry Ford Hlth, Dept Pathol & Lab Med, Detroit, MI USA
[2] Henry Ford Hlth, Dept Urol, Detroit, MI USA
[3] Michigan State Univ, Coll Human Med, Dept Med, E Lansing, MI USA
[4] Henry Ford Hlth, Dept Pathol & Lab Med, 2799W Grand Blvd, Detroit, MI 48202 USA
关键词
testis; sex cord-stromal; Sertoli; Leydig; germ cell; TESTIS;
D O I
10.1177/10668969231213983
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Testicular sex cord-stromal tumors are clonal neoplasms, with the majority being of Leydig cell followed by Sertoli cell origins. In Leydig cell tumors, adipocytic differentiation has been previously reported as a possible distinguishing feature, which has not been reported in other sex cord-stromal tumors. Herein, we report a case of a 48-year-old man who presented with an incidentally discovered 1.1 cm testicular mass, for which he underwent partial orchiectomy. Microscopically, the tumor showed features consistent with sex cord-stromal tumor with strong and diffuse nuclear and cytoplasmic reaction for B-catenin immunohistochemistry, supporting the diagnosis of Sertoli cell tumor. A novel adipocytic differentiation, reported previously in Leydig cell tumors, was present in this tumor.
引用
收藏
页码:1149 / 1153
页数:5
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