Retinal phototoxicity after macular hole surgery in a patient under paclitaxel

被引：2
|
作者：
Ruiz-Moreno, Jose M. [1 ,2 ,3 ]
Garcia-Zamora, Maria [1 ]
Ruiz-Medrano, Jorge [1 ,3 ]
机构：
[1] Puerta Hierro Majadahonda Univ Hosp, C Manuel Falla 1, Majadahonda 28222, Madrid, Spain
[2] Castilla La Mancha Univ, Dept Ophthalmol, Albacete, Spain
[3] Miranza Corp, Ocular Microsurg Inst IMO, Madrid, Spain
来源：
BMC OPHTHALMOLOGY | 2023年 / 23卷 / 01期
关键词：
Macular phototoxicity; Paclitaxel; Vitrectomy;
D O I：
10.1186/s12886-023-03086-x
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
BackgroundThe purpose is to report the second case, to our knowledge, of suspected paclitaxel-induced phototoxic maculopathy following pars plana vitrectomy surgery.Case presentation63-year-old phakic female who underwent an uneventful phaco-vitrectomy to treat a complete macular hole, developing macular phototoxicity in the post-operatively period that could not be explained by the surgery itself and could only be attributed to a possible photosensitization induced by the previous use of paclitaxel.ConclusionsThe use of paclitaxel has been widely extended as a chemotherapy drug to treat breast cancer. It works by altering the intracellular microtubular reorganization and, based on this mechanism of action, photosensitivity has been previously described. We report a case of suspected paclitaxel-induced macular phototoxicity following ocular endoillumination during vitrectomy surgery.
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页数：7
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