Valproic acid-induced eosinophilic pleural effusion: An uncommon occurrence

被引：1

作者：

Bhardwaj, Manisha ^{[1
]}

Himral, Pratibha ^{[2
]}

Kashyap, Surender ^{[3
]}

机构：

[1] Shri Lal Bahadur Shastri Govt Med Coll & Hosp, Dept Pulm Med, Mandi, Himachal Prades, India

[2] Shri Lal Bahadur Shastri Govt Med Coll & Hosp, Dept Gen Med, Mandi, Himachal Prades, India

[3] Atal Med & Res Univ, Mandi 175008, Himachal Prades, India

来源：

LUNG INDIA | 2023年 / 40卷 / 01期

关键词：

Drug reaction; eosinophilia; uncommon;

D O I：

10.4103/lungindia.lungindia_440_22

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A 43-year-old male using valproic acid (VA) for 2 years for seizure disorder presented with right-sided moderate pleural effusion. Pleural fluid analysis revealed exudative effusion with 42% eosinophils. There was no evidence of haemothorax, pneumothorax, malignancy, and parasitic infections. Suspecting a drug-related event, VA was discontinued. The patient showed clinical improvement with resolution of pleural effusion on chest radiograph three weeks later. VA is a popular drug used for variety of disorders like seizures, migraines, and schizophrenia. There is a paucity of literature on VA-induced pleural effusion. Though a rare phenomenon, clinicians should be aware of such a possibility to avoid erroneous diagnosis.

引用

页码：82 / 85

页数：4