Renal and Endocrine Responses to Arm Exercise in Persons with Cervical Spinal Cord Injury

被引:0
作者
Mukai, Yuki [1 ]
Kawasaki, Takashi [2 ]
Kamijo, Yoshi-ichiro [3 ]
Furusawa, Kazunari [4 ]
Ibusuki, Tatsuru [1 ]
Sakurai, Yuta [5 ]
Nishimura, Yukihide [1 ]
Umemoto, Yasunori [1 ]
Tajima, Fumihiro [1 ]
机构
[1] Wakayama Med Univ, Sch Med, Dept Rehabil Med, Wakayama 6418509, Japan
[2] Kyoto Prefectual Univ Med, Grad Sch Med Sci, Dept Rehabil Med, 465 Kajii Cho,Kawaramachi Hirokoji,Kamigyo Ku, Kyoto 6028566, Japan
[3] Dokkyo Med Univ, Dept Rehabil Med, Saitama Med Ctr, Saitama 3438555, Japan
[4] Kibikogen Rehabil Ctr Employment Injuries, Dept Rehabil Med, Kibichuo Cho, Okayama 7161241, Japan
[5] Nachikatsuura Balneol Town Hosp, Res Ctr Sports Med & Balneol, Tenma Nachikatuura Cho, Wakayama 6495331, Japan
关键词
ADH; glomerular filtration rate; adrenaline; sympathetic nerves; SYMPATHETIC-NERVE ACTIVITY;
D O I
10.3390/jcm12041670
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of this study was to assess renal functions and endocrine responses to arm exercise in persons with cervical spinal cord injury (CSCI) under euhydrated conditions (free drinking of water), and to determine the physiological effects of exercise on renal function in these subjects. Eleven CSCI individuals (spinal lesions between C6 and C8, American Spinal Injury Association impairment scale A) and nine able-bodied (AB) persons rested for 30 min before performing 30 min arm-crank ergometer exercises at 50% of their maximum oxygen consumption, followed by 60-min of rest/recovery. Urine and blood samples were collected before and immediately after the exercise and recovery period. The CSCI patients showed no increase in plasma adrenaline and plasma renin activity compared with the AB controls, but showed similar changes in plasma aldosterone and the plasma antidiuretic hormone in response to the exercise. Creatinine clearance, osmolal clearance, free water clearance, and the fractional excretion of Na+ did not change during exercise in both groups of subjects, however free water clearance in the CSCI group was higher than in the AB group throughout the study. These findings suggested that activated plasma aldosterone without an increase in adrenaline or renin activity during exercise in CSCI individuals may reflect an adaptation to the disturbance of the sympathetic nervous system to compensate for renal function. As a result, no adverse effects of exercise on renal function in CSCI patients were observed.
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页数:8
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