Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview

被引：15

作者：

Berzina, Laima ^{[1
]}

Mierina, Inese ^{[1
]}

机构：

[1] Riga Tech Univ, Inst Technol Organ Chem, Fac Mat Sci & Appl Chem, LV-1048 Riga, Latvia

来源：

MOLECULES | 2023年 / 28卷 / 17期

关键词：

antiradical activity; antioxidant activity; 1,3-dicarbonyl compound; & beta; -dicarbonyl compound; 1,3-diketone; keto-enol tautomerism; RADICAL SCAVENGING ACTIVITY; DPPH-CENTER-DOT; KETO-ENOL-TAUTOMERISM; BIOLOGICAL EVALUATION; ANTICANCER ACTIVITY; CRYSTAL-STRUCTURE; MELDRUMS ACID; CURCUMIN; MECHANISM; DERIVATIVES;

D O I：

10.3390/molecules28176203

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Free radicals and oxidants may cause various damages both to the lifeworld and different products. A typical solution for the prophylaxis of oxidation-caused conditions is the usage of various antioxidants. Among them, various classes are found-polyphenols, conjugated polyalkenes, and some sulfur and nitrogen derivatives. Regarding the active site in the molecules, a widely discussed group of compounds are 1,3-dicarbonyl compounds. Among them are natural (e.g., curcumin and pulvinic acids) and synthetic (e.g., 4-hydroxy coumarins, substituted Meldrum's acids) compounds. Herein, information about various compounds containing the 1,3-dicarbonyl moiety is covered, and their antiradical and antioxidant activity, depending on the structure, is discussed.

引用

页数：29

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