A coarse-grained molecular model of amyloid fibrils systems

被引：2

作者：

Daghash, Shaden M. ^{[1
]}

Rivas, Oscar M. Matus M. ^{[1
]}

Mezzenga, Raffaele ^{[2
,3
]}

Rey, Alejandro D. ^{[1
]}

机构：

[1] McGill Univ, Dept Chem Engn, 3610 Univ St, Montreal, PQ H3A 0C5, Canada

[2] Swiss Fed Inst Technol, Dept Hlth Sci & Technol, CH-8092 Zurich, Switzerland

[3] Swiss Fed Inst Technol, Dept Mat, CH-8093 Zurich, Switzerland

来源：

SOFT MATTER | 2023年 / 19卷 / 27期

基金：

瑞士国家科学基金会;

关键词：

LIQUID-CRYSTALS; AGGREGATION; DYNAMICS;

D O I：

10.1039/d3sm00408b

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We report a computational model for amyloid fibrils and discuss its main features and ability to match different experimental morphological characteristics. The model captures the liquid crystalline and cholesteric behaviours in short and rigid amyloid fibrils and shows promising extendibility to more complex colloidal liquid crystals.

引用

页码：5044 / 5049

页数：6

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