International consensus statement on allergy and rhinology: Allergic rhinitis-2023

被引：171

作者：

Wise, Sarah K. ^{[1
]}

Damask, Cecelia ^{[2
]}

Roland, Lauren T. ^{[3
]}

Ebert, Charles ^{[4
]}

Levy, Joshua M. ^{[1
]}

Lin, Sandra ^{[5
]}

Luong, Amber ^{[6
]}

Rodriguez, Kenneth ^{[7
]}

Sedaghat, Ahmad R. ^{[8
]}

Toskala, Elina ^{[9
]}

Villwock, Jennifer ^{[10
]}

Abdullah, Baharudin ^{[11
]}

Akdis, Cezmi ^{[12
]}

Alt, Jeremiah A. ^{[13
]}

Ansotegui, Ignacio J. ^{[14
]}

Azar, Antoine ^{[15
]}

Baroody, Fuad ^{[16
]}

Benninger, Michael S. ^{[17
]}

Bernstein, Jonathan ^{[18
]}

Brook, Christopher ^{[19
]}

Campbell, Raewyn ^{[20
]}

Casale, Thomas ^{[21
]}

Chaaban, Mohamad ^{[22
]}

Chew, Fook Tim ^{[23
]}

Chambliss, Jeffrey ^{[24
]}

Cianferoni, Antonella ^{[25
]}

Custovic, Adnan ^{[26
]}

Davis, Elizabeth Mahoney ^{[27
]}

DelGaudiomd, John M. ^{[1
]}

Ellis, Anne K. ^{[28
]}

Flanagan, Carrie ^{[1
]}

Fokkens, Wytske J. ^{[29
]}

Franzese, Christine ^{[30
]}

Greenhawt, Matthew ^{[31
]}

Gill, Amarbir ^{[32
]}

Halderman, Ashleigh ^{[33
]}

Hohlfeld, Jens M. ^{[34
]}

Incorvaia, Cristoforo

Joe, Stephanie A. ^{[35
]}

Joshi, Shyam ^{[36
]}

Kuruvilla, Merin Elizabeth ^{[37
]}

Kim, Jean ^{[38
]}

Klein, Adam M. ^{[1
]}

Krouse, Helene J. ^{[39
]}

Kuan, Edward C. ^{[40
]}

Lang, David ^{[41
]}

Larenas-Linnemann, Desiree ^{[42
]}

Laury, Adrienne M. ^{[43
]}

Lechner, Matt ^{[44
]}

Lee, Stella E. ^{[45
]}

机构：

[1] Emory Univ, Otolaryngol HNS, Atlanta, GA 30322 USA

[2] Univ Cent Florida, Otolaryngol HNS, Lake Mary, FL USA

[3] Washington Univ, Otolaryngol HNS, St Louis, MO USA

[4] Univ N Carolina, Otolaryngol HNS, Chapel Hill, NC USA

[5] Univ Wisconsin, Otolaryngol HNS, Madison, WI USA

[6] Univ Texas Houston, Otolaryngol HNS, McGovern Med Sch, Houston, TX USA

[7] Univ Hosp Cleveland, Otolaryngol HNS, Med Ctr, Cleveland, OH USA

[8] Univ Cincinnati, Otolaryngol HNS, Cincinnati, OH USA

[9] Thomas Jefferson Univ, Otolaryngol HNS, Philadelphia, PA USA

[10] Univ Kansas, Otolaryngol HNS, Kansas City, KS USA

[11] Univ Sains Malaysia, Otolaryngol HNS, Kerian, Kelantan, Malaysia

[12] Swiss Inst Allergy & Asthma Res, Immunol Infect Dis, Davos, Switzerland

[13] Univ Utah, Otolaryngol HNS, Salt Lake City, UT USA

[14] Hosp Quironsalud Bizkala, Allergy Immunol, Bilbao, Spain

[15] Johns Hopkins Univ, Allergy Immunol, Baltimore, MD USA

[16] Univ Chicago, Otolaryngol HNS, Chicago, IL USA

[17] Cleveland Clin, Otolaryngol HNS, Cleveland, OH USA

[18] Univ Cincinnati, Allergy Immunol, Cincinnati, OH USA

[19] Harvard Univ, Beth Israel Deaconess Med Ctr, Otolaryngol HNS, Boston, MA USA

[20] Macquarie Univ, Otolaryngol HNS, Sydney, NSW, Australia

[21] Univ S Florida, Allergy Immunol, Coll Med, Tampa, FL USA

[22] Case Western Reserve Univ, Cleveland Clin, Otolaryngol HNS, Cleveland, OH USA

[23] Natl Univ Singapore, Allergy Immunol Genet, Singapore, Singapore

[24] Univ Texas Southwestern, Allergy Immunol, Dallas, TX USA

[25] Childrens Hosp Philadelphia, Allergy Immunol, Philadelphia, PA USA

[26] Imperial Coll London, Pediat Allergy, London, England

[27] Boston Univ, Otolaryngol HNS, Boston, MA USA

[28] Queens Univ, Allergy Immunol, Kingston, ON, Canada

[29] Univ Amsterdam, Otorhinolaryngol, Med Ctr, Amsterdam, Netherlands

[30] Univ Missouri, Otolaryngol HNS, Columbia, MO USA

[31] Univ Colorado, Childrens Hosp Colorado, Allergy Immunol Pediat, Aurora, CO USA

[32] Univ Michigan, Otolaryngol HNS, Ann Arbor, MI USA

[33] Univ Texas Southwestern, Otolaryngol HNS, Dallas, TX USA

[34] German Ctr Lung Res, Fraunhofer Inst Toxicol & Expt Med ITEM, Hannover Med Sch, Resp Med, Hannover, Germany

[35] Univ Illinois, Otolaryngol HNS, Chicago, IL USA

[36] Oregon Hlth & Sci Univ, Allergy Immunol, Portland, OR USA

[37] Emory Univ, Allergy Immunol, Atlanta, GA USA

[38] Johns Hopkins Univ, Otolaryngol HNS, Baltimore, MD USA

[39] Univ Texas Rio Grande Valley, Otorhinolaryngol Nursing, Edinburg, TX USA

[40] Univ Calif Irvine, Otolaryngol HNS, Orange, CA USA

[41] Cleveland Clin, Allergy Immunol, Cleveland, OH USA

[42] Med Clin Fdn & Hosp, Allergy Immunol Pediat, Mexico City, DF, Mexico

[43] Bellevue ENT, Otolaryngol HNS, Bellevue, WA USA

[44] UCL, Barts Hlth NHS Trust, Otolaryngol HNS, London, England

[45] Brigham & Womens Hosp, Otolaryngol HNS, Boston, MA USA

[46] Univ Calif San Francisco, Otolaryngol HNS, San Francisco, CA USA

[47] SUNY Stony Brook, Otolaryngol HNS, Stony Brook, NY USA

[48] SUNY Upstate, Otolaryngol HNS, Syracuse, NY USA

[49] Univ Virginia, Otolaryngol HNS, Charlottesville, VA USA

[50] Ochsner Clin & Alton Ochsner Med Fdn, Otolaryngol HNS, New Orleans, LA USA

来源：

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY | 2023年 / 13卷 / 04期

关键词：

allergen extract; allergen immunotherapy; allergy; allergic rhinitis; antihistamine; asthma; atopic dermatitis; avoidance; biologic; cockroach; conjunctivitis; consensus; corticosteroid; cough; cromolyn; decongestant; eosinophilic esophagitis; environment; epicutaneous; immunotherapy; epidemiology; evidence-based medicine; food allergy; house dust mite; IgE; immunoglobulin E; inhalant allergy; leukotriene; microbiome; occupational rhinitis; omalizumab; pediatric; perennial; pet dander; pollen; probiotic; rhinitis; rhinosinusitis; saline; seasonal; sensitization; sinusitis; socioeconomic; specific IgE; subcutaneous immunotherapy; sublingual immunotherapy; systematic review; total IgE; transcutaneous immunotherapy; validated survey; QUALITY-OF-LIFE; HOUSE-DUST-MITE; AZELASTINE NASAL SPRAY; EXHALED NITRIC-OXIDE; OBSTRUCTIVE SLEEP-APNEA; PLACEBO-CONTROLLED TRIAL; SKIN-PRICK TEST; RANDOMIZED DOUBLE-BLIND; GRASS-POLLEN IMMUNOTHERAPY; ENVIRONMENTAL EXPOSURE UNIT;

D O I：

10.1002/alr.23090

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

BackgroundIn the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40 topics from the 2018 document. Originally presented topics from 2018 have also been reviewed and updated. The executive summary highlights key evidence-based findings and recommendation from the full document. MethodsICAR-Allergic Rhinitis 2023 employed established evidence-based review with recommendation (EBRR) methodology to individually evaluate each topic. Stepwise iterative peer review and consensus was performed for each topic. The final document was then collated and includes the results of this work. ResultsICAR-Allergic Rhinitis 2023 includes 10 major content areas and 144 individual topics related to AR. For a substantial proportion of topics included, an aggregate grade of evidence is presented, which is determined by collating the levels of evidence for each available study identified in the literature. For topics in which a diagnostic or therapeutic intervention is considered, a recommendation summary is presented, which considers the aggregate grade of evidence, benefit, harm, and cost. ConclusionThe ICAR-Allergic Rhinitis 2023 update provides a comprehensive evaluation of AR and the currently available evidence. It is this evidence that contributes to our current knowledge base and recommendations for patient evaluation and treatment.

引用

页码：293 / 859

页数：567

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