Recent advances in biopolymer based electrospun nanomaterials for drug delivery systems

被引:7
|
作者
Toren, Elcin [1 ,2 ,3 ]
Buzgo, Matej [2 ]
Mazari, Adnan Ahmed [1 ]
Khan, Muhammad Zaman [1 ]
机构
[1] Tech Univ Liberec, Fac Text Engn, Liberec, Czech Republic
[2] RESPILON Membranes SRO, RnD, Brno, Czech Republic
[3] Tech Univ Liberec, Fac Text Engn, 1402-2, Liberec 46117, Czech Republic
关键词
biopolymers; drug delivery systems; nanomaterials; polysaccharides; proteins; REGENERATIVE MEDICINE; ULTRAFINE FIBERS; TISSUE; NANOFIBERS; CELLULOSE; NANOPARTICLES; STRATEGIES; MORPHOLOGY; SCAFFOLDS; RELEASE;
D O I
10.1002/pat.6309
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Drug delivery systems, including liposomes, gels, prodrugs, and so forth, are used to enhance the tissue benefit of a pharmaceutical drug or conventional substance at a specific diseased site with little toxicological impact. Nanotechnology can be a rapidly developing multidisciplinary science that enables the production of polymers at the manometer scale for different medical applications. The use of biopolymers in drug delivery systems provides compatibility, biodegradability and low immunogenicity biologically. Large-scale and smaller-than-expected medication particles can be delivered using biopolymers such as silk fibroins, collagen, gelatine, and others that are easily formed into suspensions. These drug carrier systems are functional at improving drug delivery and can be used in intranasal, transdermal, dental, and ocular delivery systems. This study discusses the latest developments in drug delivery methods based on nanomaterials, mainly using biopolymers like proteins and polysaccharides.
引用
收藏
页数:13
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