Nanodiamond-drug conjugates for coating xenogenic heart valve prostheses

被引：3

作者：

Chernysheva, Maria G. ^{[1
]}

Shen, Tianyi ^{[1
]}

Chaschin, Ivan S. ^{[2
,3
]}

Badun, Gennadii A. ^{[1
]}

Vasil'ev, Viktor G. ^{[2
]}

Mikheev, Ivan, V ^{[1
]}

Bakuleva, Natalia P. ^{[3
]}

机构：

[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia

[2] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Moscow 119334, Russia

[3] AN Bakulev Natl Med Res Ctr Cardiovasc Surg, Moscow 121552, Russia

来源：

MENDELEEV COMMUNICATIONS | 2024年 / 34卷 / 01期

基金：

俄罗斯科学基金会;

关键词：

xenogenic heart valve prostheses; nanodiamonds; chitosan; amikacin; levofloxacin; calcification; BOVINE PERICARDIUM; CALCIFICATION; ADSORPTION;

D O I：

10.1016/j.mencom.2024.01.031

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multicomponent coatings of collagen-rich matrices of bovine pericardium were prepared from nanodiamonds and antibiotics, namely, amikacin, levofloxacin and chitosan. Preservation of the multilayers that consist of nanodiamonds, antimicrobial agents and chitosan on the material surface and preventing the calcification of the material were revealed.

引用

页码：104 / 106

页数：3

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