Comparison of healthcare costs before and after a STEMI: A French national health data system-based cohort study

Background: Few studies have investigated real-world healthcare costs following a myocardial infarction (MI) and, to our knowledge, none after an ST-elevation MI (STEMI) specifically. Producing such data is important in order to help evaluate the economic burden of STEMI, but also to feed economic evaluation models and eventu-ally show the economic interest of reducing STEMI incidence. The aim of this study was to estimate the healthcare cost in the year preceding and the year following a STEMI in France, in order to estimate the surplus in healthcare resource consumption after a STEMI.Methods: This study was conducted from the healthcare system perspective. The individual data from the HIBISCUS-STEMI cohort, which included patients with acute STEMI undergoing primary percutaneous coronary intervention, were matched with the French national health data system (Systeme National des Donnees de Sante, SNDS) using a probabilistic method. All expenses (in-and out-hospital) presented for reimbursement were taken into account to estimate a mean annual healthcare cost. Results: A total 258 patients from the HIBISCUS-STEMI cohort were included in this economic study. The total mean healthcare cost was estimated at euro3516 before the STEMI, and at euro9980 after the STEMI. Hospitalizations constituted the largest cost item, 27 % of the total cost before the STEMI and 41.8 % after the STEMI (Delta + 338.8 %). Follow-up and rehabilitative care represented the second largest cost item (25.9 % before and 18 % after the STEMI, Delta + 96.7 %). Treatments represented 19.4 % of the total cost before the STEMI and 17.2 % after (Delta + 150.8 %).Conclusions: This study shows a significant surplus (threefold) of healthcare resource consumption in the year following a STEMI compared to the year preceding the STEMI.(c) 2023 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.