Theoretical considerations for a left atrial pump in heart failure with preserved ejection fraction

被引:5
作者
Rosenblum, Hannah [1 ]
Brener, Michael [1 ]
Burkhoff, Daniel [2 ]
机构
[1] Columbia Univ, Irving Med Ctr, NYP Hosp, Div Cardiol,Dept Med, New York, NY 10027 USA
[2] Cardiovasc Res Fdn, New York, NY USA
关键词
Heart failure with preserved ejection fraction; Advanced heart failure; Mechanical circulatory support; Devices; PARTIAL VENTRICULAR SUPPORT; REDUCE LAP-HF; ASSIST DEVICE; SHUNT DEVICE; PRESSURE; THERAPY; PHENOTYPE; OUTCOMES;
D O I
10.1007/s10741-021-10121-w
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure with preserved ejection fraction (HFpEF) is a heterogenous group of disorders, unified by findings of elevated left atrial and left ventricular filling pressures in the setting of normal systolic function. Medical therapies for HFpEF patients are markedly limited, and these patients are often unable to tolerate conventional left ventricular assist device therapies because of small chamber size. The Synergy System (CircuLite, Inc., Saddle Brook, NJ) was a micropump-based form of mechanical circulatory support in which flow derived from the left atrium was delivered to the subclavian artery. In this review, we discuss the potential role of the Synergy left atrial pump to address the hemodynamic derangements of HFpEF.
引用
收藏
页码:273 / 280
页数:8
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