A perspective review on the biosynthesis of plant-based secondary metabolites and their application as potent drugs

被引:1
作者
Pramanik, Jhilam [1 ]
Kumar, Kash [2 ]
Rustagi, Sarvesh [3 ]
Katyal, Mehak [4 ]
Thakur, Sheetal [5 ]
Bora, Jutishna [6 ]
Malik, Sumira [6 ,7 ]
Trehan, Anchal [8 ]
Slama, Petr [9 ]
机构
[1] ITM Univ, Dept Food Technol, Gwalior, India
[2] SRM Univ, Dept Food Technol, Sonipat, India
[3] Uttaranchal Univ, Dept Food Technol, Dehra Dun, India
[4] Manav Rachna Int Inst Res & Studies MRIIRS, Dept Nutr & Dietet, Faridabad, India
[5] Chandigarh Univ, UIBT, Univ Ctr Res & Dev, Mohali, India
[6] Amity Univ, Amity Inst Biotechnol, Ranchi, Jharkhand, India
[7] Chandigarh Univ, Univ Ctr Res & Dev UCRD, Dept Biotechnol, Mohali, Punjab, India
[8] Guru Nanak Coll Pharmaceut Sci, Dept Sci, Dehra Dun, India
[9] Mendel Univ Brno, Dept Anim Morphol, Brno, Czech Republic
关键词
Secondary metabolites; Medicinal plant; Synthesis; Health bene fi ts; NATURAL-PRODUCTS; BIOACTIVE COMPOUNDS; PHYTOCHEMICAL CONSTITUENTS; MEDICINAL-PLANTS; RECENT TRENDS; WATER-STRESS; L; ANTIOXIDANT; EXPRESSION; GROWTH;
D O I
10.32604/biocell.2023.029031
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Many phytochemicals and their derived metabolites produced by plants are extensively employed in commercial goods, pharmaceutical products as well as in the environmental and medical fields. However, these secondary metabolites obtained from plants are in low amounts, and it is difficult to synthesize them at the industrial level. Despite these challenges, they may be utilized for a variety of medicinal products that are either available in the market or are being researched and tested. Secondary metabolites are complex compounds that exhibit chirality. Further, under controlled conditions with elicitors, desired secondary metabolites may be produced from plant cell cultures. This review emphasizes the various aspects of secondary metabolites including their types, synthesis, and applications as medicinal products. The article aims to promote the use of plant secondary metabolites in the management and treatment of various diseases.
引用
收藏
页码:541 / 557
页数:17
相关论文
共 136 条
  • [1] Abdalla MA, 2019, J APPL BOT FOOD QUAL, V92, P204, DOI [10.5073/JABFQ.2019.092.029, 10.5073/JABFQ.2019.092.02]
  • [2] Enzymatic synthesis of cyclic triterpenes
    Abe, Ikuro
    [J]. NATURAL PRODUCT REPORTS, 2007, 24 (06) : 1311 - 1331
  • [3] Bioactive compounds and their libraries: An insight into prospective phytotherapeutics approach for oral mucocutaneous cancers
    Adeola, Henry A.
    Bano, Afsareen
    Vats, Ravina
    Vashishtha, Amit
    Verma, Deepika
    Kaushik, Deepak
    Mittal, Vineet
    Rahman, Md. Habibur
    Najda, Agnieszka
    Albadrani, Ghadeer M.
    Sayed, Amany A.
    Farouk, Sameh M.
    Hassanein, Emad H. M.
    Akhtar, Muhammad Furqan
    Saleem, Ammara
    Abdel-Daim, Mohamed M.
    Bhardwaj, Rashmi
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2021, 141
  • [4] Ahmed E., 2017, J. Pharmacogn. Phytochem, V6, P205
  • [5] Screening of crude extracts of six medicinal plants used in South-West Nigerian unorthodox medicine for anti-methicillin resistant Staphylococcus aureus activity
    Akinyemi K.O.
    Oladapo O.
    Okwara C.E.
    Ibe C.C.
    Fasure K.A.
    [J]. BMC Complementary and Alternative Medicine, 5 (1):
  • [6] Screening of Fruits of Seven Plants Indicated for Medicinal Use in Iraq
    Aldulaimi, Omar
    [J]. PHARMACOGNOSY MAGAZINE, 2017, 13 (50) : S189 - S195
  • [7] Del Río JA, 2014, STUD NAT PROD CHEM, V43, P145, DOI 10.1016/B978-0-444-63430-6.00005-9
  • [8] Effect of drought stress on essential oil composition of Thymus vulgaris L. (Chemotype 1, 8-cineole) from wild populations of Eastern Iberian Peninsula
    Antonio Llorens-Molina, Juan
    Vacas, Sandra
    [J]. JOURNAL OF ESSENTIAL OIL RESEARCH, 2017, 29 (02) : 145 - 155
  • [9] Arai Y., 2000, Journal of Nutrition, V130, P2243
  • [10] Discovery and resupply of pharmacologically active plant-derived natural products: A review
    Atanasov, Atanas G.
    Waltenberger, Birgit
    Pferschy-Wenzig, Eva-Maria
    Linder, Thomas
    Wawrosch, Christoph
    Uhrin, Pavel
    Temml, Veronika
    Wang, Limei
    Schwaiger, Stefan
    Heiss, Elke H.
    Rollinger, Judith M.
    Schuster, Daniela
    Breuss, Johannes M.
    Bochkov, Valery
    Mihovilovic, Marko D.
    Kopp, Brigitte
    Bauer, Rudolf
    Dirsch, Verena M.
    Stuppner, Hermann
    [J]. BIOTECHNOLOGY ADVANCES, 2015, 33 (08) : 1582 - 1614