Microbes, metabolites and muscle: Is the gut-muscle axis a plausible therapeutic target in Duchenne muscular dystrophy?

被引:10
作者
Marullo, Anthony L. [1 ]
O'Halloran, Ken D. [1 ]
机构
[1] Univ Coll Cork, Coll Med & Hlth, Sch Med, Dept Physiol, Cork, Ireland
关键词
Duchenne muscular dystrophy; gut microbial therapies; gut-muscle axis; metabolic signalling; SKELETAL-MUSCLE; ENERGY-EXPENDITURE; KAPPA-B; RESISTANCE; RECEPTOR; ATROPHY; HEALTH; TGR5; MECHANISMS; UROLITHIN;
D O I
10.1113/EP091063
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
New FindingsWhat is the topic of this review?The contribution of gut microbial signalling to skeletal muscle maintenance and development and identification of potential therapeutic targets in progressive muscle degenerative diseases such as Duchenne muscular dystrophy.
引用
收藏
页码:1132 / 1143
页数:12
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