Decade Advance of Isatin in Three-component Reactions

被引：11

作者：

Zhang, Shuaijie ^{[1
]}

Huang, Dayun ^{[1
]}

Wu, Jinjing ^{[2
]}

Wang, Zefeng ^{[1
]}

机构：

[1] Lishui Univ, Dept Chem, 1 Xueyuan Rd, Lishui 323000, Zhejiang Provin, Peoples R China

[2] Lishui Univ, Sch Teacher Educ, 1 Xueyuan Rd, Lishui 323000, Zhejiang Provin, Peoples R China

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 12卷 / 02期

关键词：

Isatin; electrophile; three-component reactions; mechanism; ONE-POT SYNTHESIS; PYRROLIDINE-FUSED SPIROOXINDOLES; 1,3-DIPOLAR CYCLOADDITION; GREEN SYNTHESIS; HIGHLY EFFICIENT; DIASTEREOSELECTIVE SYNTHESIS; MULTICOMPONENT SYNTHESIS; AZOMETHINE YLIDES; ENANTIOSELECTIVE CONSTRUCTION; CASCADE REACTION;

D O I：

10.1002/ajoc.202200591

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Isatin is an important building block in organic synthesis. The electron-deficient carbonyl in C-3 site is similar to aldehyde. C-3 carbonyl is also able to function as the O-nucleophile. Devise methodologies about three-component reactions of isatin have been reported in this decade. This review highlights these multicomponent reactions by triggered mechanisms. We hope it will promote future research in this area.

引用

页数：16

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