Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis

被引：3

作者：

Liu, Jie ^{[1
]}

Yan, Qin ^{[2
]}

Wang, Li-Xia ^{[1
]}

He, Xiao-Ping ^{[1
]}

Hu, Hong ^{[1
]}

Liu, Yan-Chun ^{[2
]}

Li, Dan ^{[1
]}

Liu, Yan ^{[1
]}

Guo, Kai ^{[1
]}

Li, Sheng-Hong ^{[1
,2
]}

机构：

[1] Chengdu Univ Tradit Chinese Med, Innovat Inst Chinese Med & Pharm, State Key Lab Southwestern Chinese Med Resources, Chengdu 611137, Peoples R China

[2] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochemistry & Plant Resources Wes, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China

来源：

PHYTOCHEMISTRY | 2023年 / 210卷

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

Swertia pseudochinensis Hara; Gentianaceae; Secoiridoids; Anti-inflammatory activity; NATURALLY-OCCURRING IRIDOIDS; CHEMICAL-CONSTITUENTS; PART; BIOTRANSFORMATION; GENTIOPICROSIDE; BIOSYNTHESIS; GLUCOSIDES;

D O I：

10.1016/j.phytochem.2023.113642

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Detailed phytochemical investigation on the traditional Chinese medicine Swertia pseudochinensis Hara led to the isolation of ten undescribed secoiridoids and fifteen known analogs. Their structures were elucidated by extensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS). Selected isolates were assayed for their anti-inflammatory and antibacterial activities, and moderate anti-inflammatory activity via inhibiting the secretion of cytokines IL-6 and TNF-alpha in macrophages RAW264.7 induced by LPS were observed. Antibacterial activity against Staphylococcus aureus was not found at 100 mu M.

引用

页数：8

共 50 条

[41] Hepatoprotective triterpenes from traditional Tibetan medicine Potentilla anserina [J].

Morikawa, Toshio ;

Ninomiya, Kiyofumi ;

Imura, Katsuya ;

Yamaguchi, Takahiro ;

Akagi, Yoshinori ;

Yoshikawa, Masayuki ;

Hayakawa, Takao ;

Muraoka, Osamu .

PHYTOCHEMISTRY, 2014, 102 :169-181

[42] Molecular authentication of the traditional Tibetan medicinal plant Swertia mussotii [J].

Xue, Chun-Ying ;

Li, De-Zhu ;

Lu, Jin-Mei ;

Yang, Jun-Bo ;

Liu, Jian-Quan .

PLANTA MEDICA, 2006, 72 (13) :1223-1226

[43] Deer antler base as a traditional Chinese medicine: A review of its traditional uses, chemistry and pharmacology [J].

Wu, Feifei ;

Li, Huaqiang ;

Jin, Liji ;

Li, Xiaoyu ;

Ma, Yongsheng ;

You, Jiansong ;

Li, Shuying ;

Xu, Yongping .

JOURNAL OF ETHNOPHARMACOLOGY, 2013, 145 (02) :403-415

[44] SECOIRIDOIDS FROM FRAXINUS-ANGUSTIFOLIA [J].

CALIS, I ;

HOSNY, M ;

KHALIFA, T ;

NISHIBE, S .

PHYTOCHEMISTRY, 1993, 33 (06) :1453-1456

[45] From tradition to innovation: Systematic analysis of quality markers (Q-markers) in traditional Chinese medicine [J].

Mu, Jingru ;

Li, Hongwei ;

Xu, Mengwei ;

Luo, Tingting ;

Luo, Zhixiu ;

Yang, Ning ;

Xu, Delin .

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2025, 53 (05)

[46] Cytotoxic Cycloartane Triterpenes of the Traditional Chinese Medicine "Shengma" (Cimicifuga dahurica) [J].

Nian, Yin ;

Wang, Hai-Yan ;

Zhou, Lin ;

Su, Jia ;

Li, Yan ;

Qiu, Ming-Hua .

PLANTA MEDICA, 2013, 79 (01) :60-69

[47] The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine [J].

Ma, Jieyao ;

Li, Kailin ;

Shi, Silin ;

Li, Jian ;

Tang, Sunv ;

Liu, LiangHong .

FRONTIERS IN PHARMACOLOGY, 2022, 13

[48] Advances in analytical techniques and quality control of traditional Chinese medicine injections [J].

Tu, Yujia ;

Li, Linnan ;

Wang, Zhengtao ;

Yang, Li .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 206

[49] Pterocephanoside A, a new iridoid from a traditional Tibetan medicine, Pterocephalus hookeri [J].

Wang, Wen-Xiang ;

Luo, Shi-Ying ;

Wang, Yi ;

Xiang, Li ;

Liu, Xiu-Hua ;

Tang, Ce ;

Zhang, Yi .

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 23 (12) :1189-1196

[50] A xanthone glycoside from aerial parts of Swertia paniculata [J].

Pant, Neerja ;

Misra, Himanshu ;

Jain, Dharam C. .

JOURNAL OF SAUDI CHEMICAL SOCIETY, 2014, 18 (05) :551-554

← 1 2 3 4 5 →