A light-driven enzyme-free photoelectrochemical sensor based on HKUST-1 derived Cu2O/Cu@microporous carbon with g-C3N4 p-n heterojunction for ultra-sensitive detection of L-cysteine

被引:17
作者
Huang, Linzi [1 ]
Li, Jiaodi [1 ,3 ]
Wang, Yilin [1 ]
Hu, Xuan [2 ]
Shi, Kai [1 ]
Li, Chunyan [1 ]
Xie, Yixi [2 ]
Zhao, Pengcheng [1 ,3 ,5 ]
Fei, Junjie [1 ,3 ,4 ,5 ]
机构
[1] Xiangtan Univ, Coll Chem, Key Lab Environmentally Friendly Chem & Applicat, Minist Educ, Xiangtan 411105, Peoples R China
[2] Xiangtan Univ, Key Lab Green Organ Synth & Applicat Hunan Prov, Xiangtan 411105, Peoples R China
[3] Xiangtan Univ, Hunan Inst Adv Sensing & Informat Technol, Xiangtan 411105, Peoples R China
[4] East China Normal Univ, Key Lab Polar Mat & Devices, Minist Educ, Shanghai 200241, Peoples R China
[5] Xiangtan Univ, Coll Chem, Xiangtan, Peoples R China
基金
中国国家自然科学基金;
关键词
Photoelectrochemical sensor; L-cysteine; Cu2O; Microporous carbon; ULTRASENSITIVE DETERMINATION; NANOSHEETS;
D O I
10.1016/j.carbon.2023.118466
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
L-cysteine (L-Cys) plays an important role in human health as well as in the biological environment. Here, a simple physical mixing technique was used to create the p-n heterojunction by homogeneously immobilizing cuprous oxide/copper@microporous carbon (Cu2O/Cu@mC) on the surface of a sheet of g-C3N4 (CNS). Among them, the porous structure of Cu2O/Cu@mC after heat treatment is favorable for charge storage. Meanwhile, the carbon element in Cu2O/Cu@mC acts as a photosensitizer and electron mediator to extend visible light ab-sorption. Compared with bulk g-C3N4 (CNB), the sheet-like structure and high specific surface area of CNS can be used as a carrier for the binding of Cu2O/Cu@mC with L-Cys. Based on the interaction between L-Cys and Cu2O/ Cu@mC through the formation of Cu-S bonds, Cu2O/Cu@mC/CNS was proposed as a light-driven enzyme-free photoelectrochemical sensor for the detection of L-Cys. In the best case, the Cu2O/Cu@mC/GCE sensor has a low limit of detection of 1.26 x 10-9 M for L-Cys and a wide linear range (1.0 x 10-8 M -4.0 x 10-6 M). The repeatability, reproducibility, stability, selectivity and specificity of the sensor were satisfactory. In addition, the potential applicability of the proposed photoelectrochemical sensor was evaluated in tap water and human serum.
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页数:14
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共 64 条
[1]   Highly selective colorimetric cysteine sensor based on the formation of cysteine layer on copper nanoparticles [J].
Ahmed, Khan Behlol Ayaz ;
Sengan, Megarajan ;
Kumar, Suresh P. ;
Veerappan, Anbazhagan .
SENSORS AND ACTUATORS B-CHEMICAL, 2016, 233 :431-437
[2]   Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation [J].
Bloom, Seth M. ;
Mafunda, Nomfuneko A. ;
Woolston, Benjamin M. ;
Hayward, Matthew R. ;
Frempong, Josephine F. ;
Abai, Aaron B. ;
Xu, Jiawu ;
Mitchell, Alissa J. ;
Westergaard, Xavier ;
Hussain, Fatima A. ;
Xulu, Nondumiso ;
Dong, Mary ;
Dong, Krista L. ;
Gumbi, Thandeka ;
Ceasar, F. Xolisile ;
Rice, Justin K. ;
Choksi, Namit ;
Ismail, Nasreen ;
Ndung'u, Thumbi ;
Ghebremichael, Musie S. ;
Relman, David A. ;
Balskus, Emily P. ;
Mitchell, Caroline M. ;
Kwon, Douglas S. .
NATURE MICROBIOLOGY, 2022, 7 (03) :434-+
[3]   A photo-sensitive BiVO4@Bi2O3@g-C3N4 sensor for the detection of dopamine [J].
Cakar, Soner ;
Cakiroglu, Bekir ;
Sen, Sadi ;
Ozacar, Mahmut .
MICROCHEMICAL JOURNAL, 2022, 178
[4]   CuO Nanoplates for High-Performance Potassium-Ion Batteries [J].
Cao, Kangzhe ;
Liu, Huiqiao ;
Li, Wangyang ;
Han, Qingqing ;
Zhang, Zhang ;
Huang, Kejing ;
Jing, Qiangshan ;
Jiao, Lifang .
SMALL, 2019, 15 (36)
[5]   Polydopamine-sensitized WS2/black-TiO2 heterojunction for histone acetyltransferase detection with enhanced visible-light-driven photoelectrochemical activity [J].
Chen, Yan ;
Yin, Huanshun ;
Li, Fei ;
Zhou, Jie ;
Wang, Lingsong ;
Wang, Jun ;
Ai, Shiyun .
CHEMICAL ENGINEERING JOURNAL, 2020, 393
[6]   Buffer effect of In2O3 interlayer on band offset at CuO/ZnO interface for enhanced photoelectrocatalytic water splitting [J].
Chen, Ying-Chu ;
Wu, Zhi-Jie ;
Hsu, Yu-Kuei .
JOURNAL OF CATALYSIS, 2019, 370 :224-231
[7]   Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth [J].
Cramer, Shiro L. ;
Saha, Achinto ;
Liu, Jinyun ;
Tadi, Surendar ;
Tiziani, Stefano ;
Yan, Wupeng ;
Triplett, Kendra ;
Lamb, Candice ;
Alters, Susan E. ;
Rowlinson, Scott ;
Zhang, Yan Jessie ;
Keating, Michael J. ;
Huang, Peng ;
DiGiovanni, John ;
Georgiou, George ;
Stone, Everett .
NATURE MEDICINE, 2017, 23 (01) :120-127
[8]   Photoinduced Electron Transfer Modulated Photoelectric Signal: Toward an Organic Small Molecule-Based Photoelectrochemical Platform for Formaldehyde Detection [J].
Gao, Yuan ;
Yu, Zhichao ;
Huang, Lingting ;
Zeng, Yongyi ;
Liu, Xiaolong ;
Tang, Dianping .
ANALYTICAL CHEMISTRY, 2023, 95 (23) :9130-9137
[9]   Ultrasensitive non-enzymatic pesticide electrochemical sensor based on HKUST-1-derived copper oxide @ mesoporous carbon composite [J].
Gu, Chunmeng ;
Wang, Qian ;
Zhang, Li ;
Yang, Pingping ;
Xie, Yixi ;
Fei, Junjie .
SENSORS AND ACTUATORS B-CHEMICAL, 2020, 305
[10]  
Guan Y., 2023, Small, V19